Evoclin Side Effects
Please note - some side effects for Evoclin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
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For the consumer For the professional
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Side Effects of Evoclin - for the consumer
Evoclin Foam
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Evoclin Foam:
Seek medical attention right away if any of these SEVERE side effects occur when using Evoclin Foam:Burning sensation on treated areas; dry or itchy skin; headache.
TopSevere allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood/mucus in your stools; severe or persistent diarrhea; stomach cramps/pain; swelling, redness, burning, or peeling of your skin.
For the professional
Evoclin
The incidence of adverse events occurring in ≥1% of the patients in clinical studies comparing Evoclin and its vehicle is presented below:
| Adverse Event | Number (%) of Subjects | |
| Evoclin Foam | Vehicle Foam | |
| N = 439 | N = 154 | |
| Headache | 12 (3%) | 1 (1%) |
| Application site burning | 27 (6%) | 14 (9%) |
| Application site pruritus | 5 (1%) | 5 (3%) |
| Application site dryness | 4 (1%) | 5 (3%) |
| Application site reaction,not otherwise specified | 3 (1%) | 4 (3%) |
In a contact sensitization study, none of the 203 subjects developed evidence of allergic contact sensitization to Evoclin.
Orally and parenterally administered clindamycin has been associated with severe colitis, which may end fatally.
Cases of diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported as adverse reactions in patients treated with oral and parenteral formulations of clindamycin and rarely with topical clindamycin. Abdominal pain and gastrointestinal disturbances, as well as gramnegative folliculitis, have also been reported in association with the use of topical formulations of clindamycin.
TopMore resources:
Clinda-Derm Topical - Includes detailed dosage instructions.
Clindesse Vaginal - Includes detailed dosage instructions.
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