Equagesic Side Effects

Please note - some side effects for Equagesic may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Equagesic Side Effects - for the Professional

Equagesic

Body as a Whole

Fever, hypothermia, thirst.

Allergic or Idiosyncratic

Severe hypersensitivity reactions, including anaphylaxis, angioneurotic edema, anuria, asthma, bronchospasm, bullous dermatitis, chills, erythema multiforme, exfoliative erythroderma, laryngeal edema, oliguria, proctitis, purpura, Stevens-Johnson syndrome, stomatitis, and urticaria. Milder reactions are characterized by an itchy, erythematous maculopapular, or urticarial rash which may be generalized or confined to the groin. Other reactions have included acute nonthrombocytopenic purpura, adenopathy, cross-sensitivity between meprobamate/ mebutamate and meprobamate/carbromal, ecchymoses, eosinophilia, fixed-drug eruption with cross-reaction to carisoprodol, leukopenia, peripheral edema, and petechiae.

Cardiovascular

Various forms of arrhythmia, hypotension, palpitation, syncope, tachycardia, and transient ECG changes.

Central Nervous System

Agitation, ataxia, cerebral edema, coma, confusion, dizziness, drowsiness, dysphoria, euphoria, fast EEG activity, headache, impairment of visual accommodation, lethargy, overstimulation, paradoxical excitement, paresthesias, sedation, slurred speech, subdural or intracranial hemorrhage, seizures, vertigo, and weakness.

Fluid and Electrolyte

Dehydration, hyperkalemia, metabolic acidosis, and respiratory alkalosis.

Gastrointestinal

Abdominal pain, constipation, diarrhea, dyspepsia, epigastric discomfort, gastric distress, gastrointestinal bleeding, heartburn, hepatitis, nausea, pancreatitis, Reye’s syndrome, transient elevations of hepatic enzymes, ulceration and perforation, and vomiting.

Hematologic

 Agranulocytosis and aplastic anemia have been reported, although no causal relationship has been established, coagulopathy, disseminated intravascular coagulation, exacerbation of porphyric symptoms, hemolytic anemia, iron deficiency anemia, occult blood loss, prolongation of the prothrombin time, thrombocytopenia, and thrombocytopenic purpura.

Musculoskeletal

Rhabdomyolysis

Metabolism

Hyperglycemia and hypoglycemia

Reproductive

Prolonged pregnancy and labor, stillbirths, lower birth weight infants, and antepartum and postpartum bleeding.

Respiratory

Acute airway obstruction, hyperpnea, pulmonary edema, and tachypnea.

Special Senses

Hearing loss and tinnitus.

Urogenital

Interstitial nephritis, papillary necrosis, proteinuria, and renal insufficiency and failure.

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