Doxapram Side Effects

Please note - some side effects for Doxapram may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Doxapram - for the Consumer

Doxapram

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Doxapram:

Abnormal skin sensations; coughing; diarrhea; dilation of pupils; dizziness; fear; flushing; headache; hiccups; itching; nausea; sweating; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in heart rate; chest pain; disorientation; fainting; fast or irregular heartbeat; fever; hyperactivity; inability to urinate; involuntary movements; loss of bladder control; muscle spasms; seizures; severe dizziness or headache; slow breathing.

Doxapram Side Effects - for the Professional

Doxapram

Adverse reactions reported coincident with the administration of Doxapram include:

1. Central and Autonomic Nervous Systems
   Pyrexia, flushing, sweating; pruritus and paresthesia, such as a feeling of warmth, burning, or hot sensation, especially in the area of genitalia and perineum; apprehension, disorientation, pupillary dilatation, hallucinations, headache, dizziness, hyperactivity, involuntary movements, muscle spasticity, muscle fasciculations, increased deep tendon reflexes, clonus, bilateral Babinski, and convulsions.
2. Respiratory
   Dyspnea, cough, hyperventilation, tachypnea, laryngospasm, bronchospasm, hiccough, and rebound hypoventilation.
3. Cardiovascular
   Phlebitis, variations in heart rate, lowered T-waves, arrhythmias (including ventricular tachycardia and ventricular fibrillation), chest pain, tightness in chest. A mild to moderate increase in blood pressure is commonly noted and may be of concern in patients with severe cardiovascular diseases.
4. Gastrointestinal
   Nausea, vomiting, diarrhea, desire to defecate.
5. Genitourinary
   Stimulation of urinary bladder with spontaneous voiding; urinary retention. Elevations of BUN and albuminuria.
6. Hemic and Lymphatic
   Hemolysis with rapid infusion. A decrease in hemoglobin, hematocrit, or red blood cell count has been observed in postoperative patients. In the presence of pre-existing leukopenia, a further decrease in WBC has been observed following anesthesia and treatment with Doxapram hydrochloride.

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