Diphenhydramine, hydrocodone, and phenylephrine Side Effects

Please note - some side effects for Diphenhydramine, hydrocodone, and phenylephrine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects by Body System

Nervous system

Nervous system side effects have included lightheadedness, nervousness, dizziness, drowsiness, sedation, mental clouding, headache, insomnia, tremors, weakness, lethargy, hallucinations, convulsions, impairment of mental and physical performance, anxiety, fear, dysphoria, psychic dependence, itchy and prickly sensations, and mood changes.

Gastrointestinal

Gastrointestinal side effects have included difficulty swallowing, dry mouth, anorexia, nausea, vomiting, and heartburn.

Genitourinary

Genitourinary side effects have included ureteral spasm, spasm of vesicle sphincters, urinary retention, and dysuria.

Cardiovascular

Cardiovascular side effects have included pallor, tachycardia, palpitations, irregular heart beat, arrhythmias and cardiovascular collapse with hypotension.

Respiratory

Respiratory side effects have included respiratory difficulty and shortness of breath.

Ocular

Ocular side effects have included blurring of vision.

Dermatologic

Dermatologic side effects have included rare reports of dermatitis.

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