Dimetapp, Childrens Non-Drowsy Allergy ODT Side Effects

Please note - some side effects for Dimetapp, Childrens Non-Drowsy Allergy ODT may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects by Body System - for Healthcare Professionals

Applies to: oral capsule; oral syrup; oral tablet; oral tablet, chewable; oral tablet, disintegrating

Nervous system

Nervous system side effects have included headache in approximately 7% of treated patients. Usually, loratadine has not been shown to cause significant drowsiness, sedation, or impair psychomotor skills.

One study of second generation antihistamines reported cetirizine was 3.5 times more likely and acrivastine 2.8 times more likely to result in sedation than loratadine. There was no significant difference in incidence of sedation between loratadine and fexofenadine.

Cardiovascular

One study reported prolongation of the QT interval when larger than recommended (20 mg per day) doses of loratadine were administered with nefazodone (300 mg every 12 hours).

Cardiovascular side effects have included hypertension, hypotension, palpitation, supraventricular tachyarrhythmias, syncope and tachycardia.

Gastrointestinal

Gastrointestinal side effects have included rare reports of nausea and dry mouth.

Hepatic

Hepatic side effects have included rare reports of jaundice, hepatitis, and hepatic necrosis.

Two cases of necroinflammatory liver injury have been reported in patients taking loratadine. One case presented within 2 weeks of starting loratadine therapy and the other occurred 14 months after the start of therapy. Liver transplantation was necessary in one patient.

Dermatologic

Dermatologic side effects have included a case report of a fixed drug eruption.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.