Dilaudid Side Effects
Generic name: hydromorphone
Note: This document contains side effect information about hydromorphone. Some of the dosage forms listed on this page may not apply to the brand name Dilaudid.
Some side effects of Dilaudid may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to hydromorphone: oral liquid, oral tablet, oral tablet extended release
Other dosage forms:
Get emergency medical help if you have any of these signs of an allergic reaction while taking hydromorphone (the active ingredient contained in Dilaudid) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
weak or shallow breathing;
pounding heartbeats or fluttering in your chest;
wheezing, chest tightness, trouble breathing;
confusion, severe weakness or drowsiness; or
feeling like you might pass out.
Less serious side effects are more likely to occur, such as:
blurred vision, double vision;
flushing (warmth, redness, or tingly feeling);
nausea, vomiting, constipation, diarrhea, stomach pain;
sleep problems (insomnia), or strange dreams.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to hydromorphone: compounding powder, injectable powder for injection, injectable solution, intravenous solution, oral capsule extended release, oral liquid, oral tablet, oral tablet extended release, rectal suppository
Nervous system side effects have included mental depression, respiratory depression (which is sometimes fatal), stupor, delirium, somnolence, agitation, increased intracranial pressure, and dysphoria. Myoclonus has also been reported.
Opioids may result in psychotic symptoms in some patients.
Other side effects have included withdrawal symptoms which have occurred following either abrupt cessation or fast tapering of narcotic analgesics and have included agitation, restlessness, anxiety, insomnia, tremor, abdominal cramps, blurred vision, vomiting, and sweating.
Cardiovascular side effects have occurred rarely and have included hypotension, shock, and arrhythmias.
Gastrointestinal side effects have included constipation, nausea, vomiting, biliary tract spasm, and dry mouth.
Dermatologic side effects including rashes and systemic contact dermatitis have been reported rarely.
Narcotic-induced rashes may be related to direct stimulation of histamine release.
Local side effects have included redness, swelling and pain which develop at the site of subcutaneous injection of hydromorphone (the active ingredient contained in Dilaudid) Two cases of fatal neurologic events have been reported following intravenous injection of hydromorphone. In one case, a known intravenous drug abuser injected two melted hydromorphone suppositories into the right antecubital vein and suffered a stroke. In the other, a known intravenous drug abuser injected ground hydromorphone tablets and presented in an akinetic mute state and later died.
Genitourinary side effects including urinary retention have been reported for other narcotic analgesics.
More Dilaudid resources
- Dilaudid Prescribing Information (FDA)
- Dilaudid Consumer Overview
- Dilaudid Advanced Consumer (Micromedex) - Includes Dosage Information
- Dilaudid MedFacts Consumer Leaflet (Wolters Kluwer)
- Dilaudid-HP Prescribing Information (FDA)
- Dilaudid-HP MedFacts Consumer Leaflet (Wolters Kluwer)
- Dilaudid-HP Advanced Consumer (Micromedex) - Includes Dosage Information
- Exalgo Consumer Overview
- Exalgo Prescribing Information (FDA)
- Exalgo MedFacts Consumer Leaflet (Wolters Kluwer)
- Hydromorphone Prescribing Information (FDA)
- Hydromorphone Hydrochloride Monograph (AHFS DI)
- Palladone Prescribing Information (FDA)
- Palladone extended-release capsules MedFacts Consumer Leaflet (Wolters Kluwer)
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