Dilantin-125 Side Effects
Generic Name: Phenytoin
Please note - some side effects for Dilantin-125 may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
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For the consumer For the professional
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Side Effects of Dilantin-125 - for the consumer
Dilantin-125 Suspension
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Dilantin-125 Suspension:
Seek medical attention right away if any of these SEVERE side effects occur when using Dilantin-125 Suspension:Constipation; dizziness; headache; nausea; vomiting.
TopSevere allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); clumsiness or unsteadiness; confusion; dark urine; delirium; high blood sugar (increased thirst, hunger, or urination; rapid breathing; flushing; fruit-like breath odor); mental or mood changes; numbness or tingling of the hands or feet; red, swollen, blistered, or peeling skin; signs of infection (eg, fever, chills, sore throat); slurred speech; stomach pain; swollen lymph nodes; swollen or tender gums; tremor; unusual bruising or bleeding; unusual eye movements; unusual muscle movements; yellowing of the skin or eyes.
For the professional
Dilantin-125
Central Nervous System
The most common manifestations encountered with phenytoin therapy are referable to this system and are usually dose-related. These include nystagmus, ataxia, slurred speech, decreased coordination, and mental confusion. Dizziness, insomnia, transient nervousness, motor twitchings, and headaches have also been observed. There have also been rare reports of phenytoin-induced dyskinesias, including chorea, dystonia, tremor and asterixis, similar to those induced by phenothiazine and other neuroleptic drugs.
A predominantly sensory peripheral polyneuropathy has been observed in patients receiving long-term phenytoin therapy.
Gastrointestinal System
Nausea, vomiting, constipation, toxic hepatitis and liver damage.
Integumentary System
Dermatological manifestations sometimes accompanied by fever have included scarlatiniform or morbilliform rashes. A morbilliform rash (measles-like) is the most common; other types of dermatitis are seen more rarely. Other more serious forms which may be fatal have included bullous, exfoliative or purpuric dermatitis, lupus erythematosus, Stevens-Johnson syndrome, and toxic epidermal necrolysis.
Hemopoietic System
Hemopoietic complications, some fatal, have occasionally been reported in association with administration of phenytoin. These have included thrombocytopenia, leukopenia, granulocytopenia, agranulocytosis, and pancytopenia with or without bone marrow suppression. While macrocytosis and megaloblastic anemia have occurred, these conditions usually respond to folic acid therapy. Lymphadenopathy including benign lymph node hyperplasia, pseudolymphoma, lymphoma, and Hodgkin's disease have been reported.
Connective Tissue System
Coarsening of the facial features, enlargement of the lips, gingival hyperplasia, hypertrichosis, and Peyronie's disease.
Immunologic
Hypersensitivity syndrome (which may include, but is not limited to, symptoms such as arthralgias, eosinophilia, fever, liver dysfunction, lymphadenopathy or rash), systemic lupus erythematosus, periarteritis nodosa and immunoglobulin abnormalities.
TopMore resources:
Dilantin Kapseals Extended-Release Capsules
Dilantin Infatabs Chewable Tablets
Dilantin-125 - Includes detailed dosage instructions.
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