Dextromethorphan, phenylephrine, and pyrilamine Side Effects

Please note - some side effects for Dextromethorphan, phenylephrine, and pyrilamine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects by Body System - for Healthcare Professionals

Applies to: oral liquid; oral suspension; oral suspension, extended release; oral syrup; oral tablet, chewable; oral tablet, chewable, extended release

Cardiovascular

Cardiovascular side effects including arrhythmias, hypertension, hypotension, and palpitations have been reported.

Nervous system

Nervous system side effects including coordination disturbances, drowsiness, dysphoria, euphoria, headache, insomnia, irritability, nervousness, sedation, and seizures have been reported.

Dermatologic

Dermatologic side effects including photosensitivity, pruritus, rash, and urticaria have been reported.

Gastrointestinal

Gastrointestinal side effects including constipation, diarrhea, epigastric discomfort, nausea, vomiting, and xerostomia have been reported.

Genitourinary

Genitourinary side effects including difficult urination and urinary frequency have been reported.

Hematologic

Hematologic side effects including agranulocytosis, hemolytic anemia, and thrombocytopenia have been reported.

Musculoskeletal

Neuromuscular side effects including tremor and weakness have been reported.

Ocular

Ocular side effects including visual disturbances have been reported.

Respiratory

Respiratory side effects including shortness of breath and wheezing have been reported.

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