Dexamethasone / neomycin / polymyxin b ophthalmic Side Effects
Medically reviewed by Drugs.com. Last updated on Dec 4, 2023.
Applies to dexamethasone/neomycin/polymyxin b ophthalmic: ophthalmic ointment, ophthalmic suspension.
Serious side effects
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Change in eyesight, eye pain, or very bad eye irritation.
Other side effects
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Eye irritation.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
For Healthcare Professionals
Applies to dexamethasone/neomycin/polymyxin b ophthalmic: ophthalmic ointment, ophthalmic suspension.
General
The most frequently reported side effects were ocular discomfort, keratitis, eye irritation, and allergic sensitization.[Ref]
Ocular
Uncommon (0.1% to 1%): Keratitis, intraocular pressure increased, vision blurred, photophobia, mydriasis, eyelid ptosis, eye pain, eye swelling, eye pruritus, ocular discomfort, foreign body sensation, eye irritation, ocular hyperemia, lacrimation increased
Frequency not reported: Corneal thinning, ulcerative keratitis
Dexamethasone:
Frequency not reported: Intraocular pressure increased, glaucoma, visual acuity reduced, visual field defect, posterior subcapsular cataract formation, globe perforation, keratitis, conjunctivitis, corneal ulcer, conjunctival hyperemia, optic nerve damage, wound healing delayed[Ref]
Immunologic
Uncommon (0.1% to 1%): Hypersensitivity
Frequency not reported: Allergic sensitization[Ref]
Nervous system
Frequency not reported: Headache[Ref]
Other
Frequency not reported: Secondary ocular infection developed, fungal infection developed[Ref]
Dermatologic
Frequency not reported: Stevens-Johnson syndrome
More about dexamethasone / neomycin / polymyxin b ophthalmic
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- Drug class: ophthalmic steroids with anti-infectives
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Patient resources
- Dexamethasone, neomycin, and polymyxin B ophthalmic drug information
- Neomycin, polymyxin b, and dexamethasone (Advanced Reading)
- Neomycin, Polymyxin B, and Dexamethasone Eye Drops
- Neomycin, Polymyxin B, and Dexamethasone Eye Ointment
Other brands
Professional resources
- Neomycin, Polymyxin B, Dexamethasone prescribing information
- Neomycin,Polymyxin B,Dexamethasone Ointment (FDA)
Other brands
Related treatment guides
References
1. Product Information. Maxitrol (dexamethasone/neomycin/polymyxin B ophthalmic). Alcon Laboratories Inc. PROD.
2. Cerner Multum, Inc. UK Summary of Product Characteristics.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
