Desoximetasone topical Side Effects
Some side effects of desoximetasone topical may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to desoximetasone topical: topical application cream, topical application gel/jelly, topical application ointment, topical application spray
Along with its needed effects, desoximetasone topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking desoximetasone topical:Rare
- Flushing or redness of the skin
- redness, blistering, peeling, or loosening of the skin
- unusually warm skin
- Blistering, burning, crusting, dryness, or flaking of the skin
- itching, scaling, severe redness, soreness, or swelling of the skin
- redness and scaling around the mouth
- thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (eg, between the fingers)
- thinning, weakness, or wasting away of the skin
Some side effects of desoximetasone topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Rare
- Burning, itching, and pain in hairy areas, or pus at the root of the hair
- Acne or pimples
- burning and itching of the skin with pinhead-sized red blisters
- increased hair growth on the forehead, back, arms, and legs
- lightening of normal skin color
- lightening of treated areas of dark skin
- reddish purple lines on the arms, face, legs, trunk, or groin
- softening of the skin
For Healthcare Professionals
Applies to desoximetasone topical: compounding powder, topical cream, topical gel, topical ointment, topical spray
Endocrine side effects have rarely included suppression of the hypothalamic-pituitary-adrenal axis. This suppression was more likely when higher potency topical corticosteroids were used over extensive areas and when occlusive dressings were used.
Local side effects have commonly included burning, itching, and irritation, especially if applied to denuded skin. Adverse reactions associated with the topical spray include application site dryness, irritation, and pruritus. Long-term use of topical corticosteroids has been associated with skin atrophy and thinning, striae, telangiectasia, subcutaneous hemorrhage, and easy bruising and bleeding. Topical corticosteroid use may also inhibit local immune response, rendering the skin more susceptible to infections. Folliculitis and allergic contact dermatitis have been occasionally reported.
Skin atrophy may become evident within one to two months of use and is due to the inhibitory effect of corticosteroids on collagen formation. Skin on the face, axillae, and groin appear to be most susceptible to the adverse, long-term effects of topical desoximetasone. Use of high potency topical corticosteroids on these areas should be minimized or avoided.
Perioral dermatitis or rosacea-like dermatitis has occurred in patients with seborrheic skin type treated with potent topical corticosteroids. This condition may flare temporarily upon discontinuation of topical steroids, prompting patients to continue their use. If topical corticosteroids are discontinued, this flare and the initial dermatitis generally resolves over a few weeks.
More desoximetasone topical resources
- desoximetasone topical Concise Consumer Information (Cerner Multum)
- Topicort Prescribing Information (FDA)
- Topicort Monograph (AHFS DI)
- Topicort Advanced Consumer (Micromedex) - Includes Dosage Information
- Topicort cream MedFacts Consumer Leaflet (Wolters Kluwer)
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