Desoximetasone topical Side Effects

Not all side effects for desoximetasone topical may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to desoximetasone topical: topical application cream, topical application gel/jelly, topical application ointment, topical application spray

In addition to its needed effects, some unwanted effects may be caused by desoximetasone topical. In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking desoximetasone topical:

Rare
  • Flushing or redness of the skin
  • redness, blistering, peeling, or loosening of the skin
  • unusually warm skin
Incidence not known
  • Blistering, burning, crusting, dryness, or flaking of the skin
  • irritation
  • itching, scaling, severe redness, soreness, or swelling of the skin
  • redness and scaling around the mouth
  • thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (eg, between the fingers)
  • thinning, weakness, or wasting away of the skin

Some of the side effects that can occur with desoximetasone topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Rare
  • Burning, itching, and pain in hairy areas, or pus at the root of the hair
Incidence not known
  • Acne or pimples
  • burning and itching of the skin with pinhead-sized red blisters
  • increased hair growth on the forehead, back, arms, and legs
  • lightening of normal skin color
  • lightening of treated areas of dark skin
  • reddish purple lines on the arms, face, legs, trunk, or groin
  • softening of the skin

For Healthcare Professionals

Applies to desoximetasone topical: compounding powder, topical cream, topical gel, topical ointment, topical spray

General

The most commonly reported side effects were application site dryness, application site irritation, and application site pruritus.[Ref]

Endocrine

Frequency not reported: Hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome[Ref]

Dermatologic

Frequency not reported: Folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, miliaria[Ref]

Local

Common (1% to 10%): Application site dryness, application site irritation, application site pruritus
Frequency not reported: Burning, itching[Ref]

Metabolic

Frequency not reported: Hyperglycemia, latent diabetes mellitus[Ref]

References

1. "Product Information. Topicort (desoximetasone topical)." Hoechst Marioin-Roussel Inc, Kansas City, MO.

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