DesOwen Side Effects

Generic name: desonide topical

Note: This document contains side effect information about desonide topical. Some of the dosage forms listed on this page may not apply to the brand name DesOwen.

Some side effects of DesOwen may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to desonide topical: compounding powder, topical cream, topical foam, topical gel, topical kit, topical lotion, topical ointment

Get emergency medical help if you have any of these signs of an allergic reaction while taking desonide topical (the active ingredient contained in DesOwen) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing desonide topical through your skin, such as:

• blurred vision, or seeing halos around lights;

• mood changes;

• sleep problems (insomnia);

• weight gain, puffiness in your face; or

• muscle weakness, feeling tired.

Less serious side effects of desonide topical may include:

• mild skin itching, redness, burning, or peeling;

• dryness or scaly skin;

• thinning or softening of your skin;

• skin rash or irritation around your mouth;

• swollen hair follicles;

• changes in color of treated skin;

• blisters, pimples, or crusting of treated skin; or

• stretch marks.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

For Healthcare Professionals

Applies to desonide topical: compounding powder, topical cream, topical foam, topical gel, topical kit, topical lotion, topical ointment

Endocrine

Endocrinologic side effects of topical corticosteroids have been rare. Rarely, the hypothalamic-pituitary-adrenal axis has been suppressed. This suppression was more likely when higher potency topical steroids were used over extensive areas and when occlusive dressings were used.

Local

Skin on the face, axillae, and groin appear to be most susceptible to the adverse, long-term effects of topical steroids.

Topical corticosteroid use may inhibit local immune response rendering the skin more susceptible to infections. Folliculitis has occasionally been reported.

Perioral dermatitis or rosacea-like dermatitis has occurred in patients treated with potent topical corticosteroids who are of seborrheic skin type. This condition may flare temporarily upon discontinuation of topical steroids, prompting patients to continue their use. If topical corticosteroids are discontinued, this flare and the initial dermatitis generally resolves over a few weeks.

Local side effects have commonly included burning, itching, or irritation, especially when applied to denuded skin or with occlusive dressings. Long-term use of topical corticosteroids has resulted in skin atrophy and thinning, and the development of striae, telangiectasia, subcutaneous hemorrhage, and easy bruising and bleeding. Allergic contact dermatitis has been occasionally reported.

General

The use of low potency topically applied corticosteroids has been generally well tolerated.

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