Desflurane Side Effects
Some side effects of desflurane may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to desflurane: inhalation liquid, inhalation solution
Along with its needed effects, desflurane may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Some side effects of desflurane may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- nausea or vomiting
- irritated or red eyes
- nervousness and restlessness
- sore throat
For Healthcare Professionals
Applies to desflurane: inhalation liquid
Respiratory side effects including coughing (34%), breathholding (up to 30%), apnea (15%), increased secretions, laryngospasm, oxyhemoglobin desaturation, pharyngitis, increased cough, dyspnea, respiratory arrest, respiratory failure, respiratory distress, bronchospasm, hemoptysis, and hypoxia have been reported.
Gastrointestinal side effects including nausea (27%), vomiting (16%), acute pancreatitis, and abdominal pain have been reported.
Cardiovascular side effects including bradycardia, hypertension, nodal arrhythmia, tachycardia, arrhythmia, bigeminy, abnormal electrocardiogram, myocardial ischemia, vasodilation, hemorrhage, cardiac arrest, Torsade de pointes, ventricular failure, ventricular hypokinesia, malignant hypertension, hypotension,
and myocardial infarct have been reported.
Nervous system side effects including increased salivation, agitation, convulsion, and dizziness have been reported.
Hepatic side effects including hepatitis, hepatic failure, hepatic necrosis, cytolytic hepatitis, cholestasis, jaundice, abnormal hepatic function, liver disorder, increased transaminases, increased alanine aminotransferase, and increased aspartate aminotransferase
have been reported.
General side effects including shock, malignant hyperthermia, asthenia, malaise, headache, and fever have been reported.
Ocular side effects including conjunctivitis (conjunctival hyperemia) and ocular icterus have been reported.
Metabolic side effects including hyperkalemia, hypokalemia, metabolic acidosis, and increased creatinine phosphokinase have been reported.
Musculoskeletal side effects including myalgia and rhabdomyolysis have been reported.
Dermatologic side effects including urticaria, erythema, and pruritus have been reported.
Hematologic side effects including coagulopathy have been reported.
More desflurane resources
- desflurane Inhalation, oral/nebulization Advanced Consumer (Micromedex) - Includes Dosage Information
- Suprane Prescribing Information (FDA)
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