Desflurane Side Effects

Not all side effects for desflurane may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to desflurane: inhalation liquid, inhalation solution

In addition to its needed effects, some unwanted effects may be caused by desflurane. In the event that any of these side effects do occur, they may require medical attention.

Some of the side effects that can occur with desflurane may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common
  • Coughing
  • nausea or vomiting
Less common or rare
  • Dizziness
  • headache
  • irritated or red eyes
  • nervousness and restlessness
  • sore throat

For Healthcare Professionals

Applies to desflurane: inhalation liquid

Respiratory

Respiratory side effects including coughing (34%), breathholding (up to 30%), apnea (15%), increased secretions, laryngospasm, oxyhemoglobin desaturation, pharyngitis, increased cough, dyspnea, respiratory arrest, respiratory failure, respiratory distress, bronchospasm, hemoptysis, and hypoxia have been reported.

Gastrointestinal

Gastrointestinal side effects including nausea (27%), vomiting (16%), acute pancreatitis, and abdominal pain have been reported.

Cardiovascular

Cardiovascular side effects including bradycardia, hypertension, nodal arrhythmia, tachycardia, arrhythmia, bigeminy, abnormal electrocardiogram, myocardial ischemia, vasodilation, hemorrhage, cardiac arrest, Torsade de pointes, ventricular failure, ventricular hypokinesia, malignant hypertension, hypotension,
and myocardial infarct have been reported.

Nervous system

Nervous system side effects including increased salivation, agitation, convulsion, and dizziness have been reported.

Hepatic

Hepatic side effects including hepatitis, hepatic failure, hepatic necrosis, cytolytic hepatitis, cholestasis, jaundice, abnormal hepatic function, liver disorder, increased transaminases, increased alanine aminotransferase, and increased aspartate aminotransferase
have been reported.

General

General side effects including shock, malignant hyperthermia, asthenia, malaise, headache, and fever have been reported.

Ocular

Ocular side effects including conjunctivitis (conjunctival hyperemia) and ocular icterus have been reported.

Metabolic

Metabolic side effects including hyperkalemia, hypokalemia, metabolic acidosis, and increased creatinine phosphokinase have been reported.

Musculoskeletal

Musculoskeletal side effects including myalgia and rhabdomyolysis have been reported.

Dermatologic

Dermatologic side effects including urticaria, erythema, and pruritus have been reported.

Hematologic

Hematologic side effects including coagulopathy have been reported.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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