Desflurane Side Effects
Not all side effects for desflurane may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to desflurane: inhalation liquid, inhalation solution
In addition to its needed effects, some unwanted effects may be caused by desflurane. In the event that any of these side effects do occur, they may require medical attention.
Some of the side effects that can occur with desflurane may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common
- nausea or vomiting
- irritated or red eyes
- nervousness and restlessness
- sore throat
For Healthcare Professionals
Applies to desflurane: inhalation liquid
Respiratory side effects including coughing (34%), breathholding (up to 30%), apnea (15%), increased secretions, laryngospasm, oxyhemoglobin desaturation, pharyngitis, increased cough, dyspnea, respiratory arrest, respiratory failure, respiratory distress, bronchospasm, hemoptysis, and hypoxia have been reported.[Ref]
Gastrointestinal side effects including nausea (27%), vomiting (16%), acute pancreatitis, and abdominal pain have been reported.[Ref]
Cardiovascular side effects including bradycardia, hypertension, nodal arrhythmia, tachycardia, arrhythmia, bigeminy, abnormal electrocardiogram, myocardial ischemia, vasodilation, hemorrhage, cardiac arrest, Torsade de pointes, ventricular failure, ventricular hypokinesia, malignant hypertension, hypotension,
and myocardial infarct have been reported.[Ref]
Nervous system side effects including increased salivation, agitation, convulsion, and dizziness have been reported.[Ref]
Hepatic side effects including hepatitis, hepatic failure, hepatic necrosis, cytolytic hepatitis, cholestasis, jaundice, abnormal hepatic function, liver disorder, increased transaminases, increased alanine aminotransferase, and increased aspartate aminotransferase
have been reported.
General side effects including shock, malignant hyperthermia, asthenia, malaise, headache, and fever have been reported.[Ref]
Ocular side effects including conjunctivitis (conjunctival hyperemia) and ocular icterus have been reported.[Ref]
Metabolic side effects including hyperkalemia, hypokalemia, metabolic acidosis, and increased creatinine phosphokinase have been reported.[Ref]
Musculoskeletal side effects including myalgia and rhabdomyolysis have been reported.[Ref]
Dermatologic side effects including urticaria, erythema, and pruritus have been reported.[Ref]
Hematologic side effects including coagulopathy have been reported.
1. "Product Information. Suprane (desflurane)." Baxter Pharmaceutical Products, Inc, New Providence, NJ.
More about desflurane
- Other brands: Suprane
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