Cyanokit Side Effects
Generic Name: hydroxocobalamin
Note: This page contains information about the side effects of hydroxocobalamin. Some of the dosage forms included on this document may not apply to the brand name Cyanokit.
Not all side effects for Cyanokit may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to hydroxocobalamin: kit
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur while taking hydroxocobalamin (the active ingredient contained in Cyanokit)
Acne-like rash; headache; nausea; red-colored urine; skin redness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody stools; chest discomfort; dizziness; dryness or tightness of the throat; eye irritation, redness, or swelling; fast or irregular heartbeat; flushing; memory problems; pain or redness at the injection site; restlessness; severe or persistent diarrhea, nausea, vomiting, or stomach pain; severe or persistent headache; shortness of breath; swelling of the ankles or feet; trouble swallowing.
For Healthcare Professionals
Applies to hydroxocobalamin: compounding powder, injectable solution, intravenous powder for injection
Gastrointestinal side effects have included mild transient diarrhea and nausea.[Ref]
Other side effects have included itching and feeling of swelling of the entire body.[Ref]
Dermatologic side effects have included transitory exanthema and erythema.[Ref]
Hypersensitivity side effects have rarely included anaphylactic reactions.[Ref]
Local side effects have included infusion site reaction and pain with injection.[Ref]
Renal side effects have included chromaturia.
Cardiovascular side effects, following intravenous administration, have included increased blood pressure.[Ref]
1. "Product Information. Hydro-Cobex (hydroxocobalamin)." Major Pharmaceuticals Inc, Rosemont, IL.
2. "Product Information. Cyanokit (hydroxocobalamin)." Meridian Medical Technologies Inc, Columbia, MD.
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