Cuvposa Side Effects

Generic name: glycopyrrolate

Note: This document contains side effect information about glycopyrrolate. Some of the dosage forms listed on this page may not apply to the brand name Cuvposa.

Some side effects of Cuvposa may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to glycopyrrolate: oral solution, oral tablet

Get emergency medical help if you have any of these signs of an allergic reaction while taking glycopyrrolate (the active ingredient contained in Cuvposa) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using glycopyrrolate and call your doctor at once if you have a serious side effect such as:

• severe constipation, severe stomach pain and bloating;

• diarrhea (especially if you have a colostomy or ileostomy);

• feeling like you might pass out;

• feeling very thirsty or hot, being unable to urinate, heavy sweating, weak pulse, or hot and dry skin; or

• dry diapers, fussiness, or excessive crying in a child taking glycopyrrolate.

Less serious side effects of glycopyrrolate may include:

• dry mouth;

• vomiting;

• mild constipation;

• stuffy nose, sinus pain; or

• flushing (warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to glycopyrrolate: injectable solution, oral solution, oral tablet

Nervous system

Nervous system side effects have included headache, nervousness, drowsiness, dizziness, insomnia, and mental confusion. The elderly appear to be more prone to the anticholinergic effects of glycopyrrolate (the active ingredient contained in Cuvposa) on the CNS. Seizures have been reported from postmarketing experience.

Cardiovascular

Cardiovascular side effects have included tachycardia and palpitations. In addition, cardiac arrhythmias, cardiac arrest, hypertension, and hypotension have been reported from postmarketing experience.

Gastrointestinal

Gastrointestinal side effects have included dry mouth, nausea, vomiting, constipation, and feeling bloated.

Genitourinary

Genitourinary side effects have included urinary hesitancy, urinary retention, and impotence.

Ocular

Ocular side effects have included blurred vision, increased ocular tension, cycloplegia, and dilatation of the pupil.

Endocrine

Endocrine side effects have included suppression of lactation.

Dermatologic

Dermatologic side effects have included dry mucous membranes and decreased sweating.

General

General side effects have included weakness, hyperpyrexia, and a loss of taste.

Hypersensitivity

Hypersensitivity side effects have included urticaria and other dermal manifestations.

Immunologic

Immunologic side effects have included anaphylaxis.

Local

Local side effects have included pruritus, edema, erythema, and pain at the injection site.

Respiratory

Respiratory side effects have included nasal congestion, nasal dryness, and sinusitis.

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