Cutivate Cream Side Effects
Please note - some side effects for Cutivate Cream may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
Side Effects by Body System - for Healthcare Professionals
Applies to: topical cream; topical lotion; topical ointment
Skin atrophy may become evident within one to two months of use and is due to the inhibitory effect of corticosteroids on collagen formation. Skin on the face, axilla, and groin are most susceptible to the adverse long-term effects of topical corticosteroids. Use of high potency topical corticosteroids on these areas should be minimized or avoided.
Topical corticosteroid use may suppress local immune responses, rendering the skin more susceptible to infections. Folliculitis has occasionally been reported.
Perioral dermatitis or rosacea like dermatitis has occurred in patients treated with potent topical corticosteroids who are of seborrheic skin type. This condition may flare temporarily upon discontinuation of topical steroids, prompting patients to continue their use. If topical corticosteroids are discontinued, this flare and the initial dermatitis generally resolve over a few weeks.
Worsening of psoriasis has occurred in a few patients.
Local adverse effects have included burning, itching, dryness, redness, or irritation, especially if applied to denuded skin. Also, acneiform eruptions, folliculitis, hypopigmentation, blisters, hypertrichosis, and infection have been reported. Long-term use of topical corticosteroids may result in skin atrophy and thinning, and the development of striae, telangiectasia, subcutaneous hemorrhage, and easy bruising and bleeding. Allergic contact dermatitis has been reported.
Endocrine side effects have rarely included symptoms of hypothalamic-pituitary-adrenal (HPA) axis suppression. These effects are more likely when higher potency topical corticosteroids are used over extensive areas and when occlusive dressings are used. HPA axis suppression has been reported with topical fluticasone when used at doses of 30 grams per day on patients with diseased skin.
Nervous system side effects have included lightheadedness in less than 1% of patients treated.
Dermatologic side effects have included burning and pruritus at the site of application. Postmarketing experience has included reports of erythema, edema/swelling, bleeding, and a lack of efficacy.
In a controlled study, the incidence of burning and pruritus occurred in 6% of both fluticasone treated patients and those who received vehicle only.Top
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