Cromolyn Side Effects
Not all side effects for cromolyn may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to cromolyn: oral capsule, oral solution
Other dosage forms:
In addition to its needed effects, some unwanted effects may be caused by cromolyn. In the event that any of these side effects do occur, they may require medical attention.
You should check with your doctor immediately if any of these side effects occur when taking cromolyn:Rare
- difficulty in swallowing
- hives or itching of skin
- swelling of face, lips, or eyelids
- wheezing or difficulty in breathing
If any of the following side effects occur while taking cromolyn, check with your doctor or nurse as soon as possible:Less common
- Skin rash
Some of the side effects that can occur with cromolyn may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common
Note: If the above side effects occur in patients with mastocytosis, they are usually only temporary and could be symptoms of the disease.
- Abdominal pain
- muscle pain
- trouble in sleeping
For Healthcare Professionals
Applies to cromolyn: compounding powder, inhalation aerosol with adapter, inhalation solution, nasal spray, oral capsule, oral solution
Hypersensitivity reactions have included anaphylaxis. Hypersensitivity side effects have been reported to develop after weeks to years of use.
Respiratory side effects have included throat irritation and transient cough and bronchospasm after inhalation of cromolyn powder by Spinhaler. Nasal congestion has been associated with cromolyn use. Pulmonary infiltrates and pulmonary granulomatosis have been rarely reported. Wheezing and chest tightness following cromolyn use have preceded more serious allergic reactions.
Throat irritation may be relieved by drinking water before and after inhalation of cromolyn. Use of a beta-2 agonist prior to cromolyn inhalation may relieve cough and bronchospasm.
Hematologic side effects have included leukocytosis and eosinophilia.
Genitourinary side effects have included urinary burning and irritation.
Dermatologic side effects have included facial or generalized dermatitis, urticaria, and rarely, vasculitis.
Gastrointestinal side effects have been reported with inhaled cromolyn, including nausea, vomiting, and rarely, esophagitis. Symptoms of lactose intolerance have been reported in a patient with lactase deficiency receiving cromolyn capsules by inhalation.
Hepatic side effects have included liver disease, with eosinophilic infiltrates, in association with eosinophilia.
Cardiovascular side effects have included a single case report of cardiac tamponade associated with eosinophilia.
Musculoskeletal system side effects have rarely included myositis, which involved the lower extremities resulting in pain and fatigue.
More about cromolyn
- Cromolyn aerosol solution
- Cromolyn concentrate
- Cromolyn nebulizer solution
- Cromolyn sodium
- Cromolyn sodium inhalation
- More (3) »
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