Cortisone Acetate Side Effects

Generic Name: cortisone,Cortisone

Please note - some side effects for Cortisone Acetate may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

For the professional

Cortisone Acetate

Fluid and electrolyte disturbances

• Sodium retention
• Potassium loss
• Fluid retention
• Hypokalemic alkalosis
• Congestive heart failure in susceptible patients
• Hypertension

Musculoskeletal

• Muscle weakness
• Vertebral compression fractures
• Steroid myopathy
• Aseptic necrosis of femoral and humeral heads
• Loss of muscle mass
• Osteoporosis
• Tendon rupture, particularly of the Achilles tendon
• Pathologic fracture of long bones

Gastrointestinal

• Peptic ulcer with possible perforation and hemorrhage
• Abdominal distention
• Ulcerative esophagitis
• Pancreatitis
• Increases in alanine transaminase (ALT, SGPT), aspartate transaminase (AST, SGOT) and alkaline phosphatase have been observed following corticosteroid treatment. These changes are usually small, not associated with any clinical syndrome and are reversible upon discontinuation.

Dermatologic

• Impaired wound healing
• Facial erythema
• Thin fragile skin
• Increased sweating
• Petechiae and ecchymoses
• May suppress reactions to skin tests

Neurological

• Increased intracranial pressure with papilledema (pseudotumor cerebri) usually after treatment
• Convulsions
• Vertigo
• Headache

Endocrine

• Menstrual irregularities
• Suppression of growth in children
• Development of Cushingoid state
• Decreased carbohydrate tolerance
• Secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery or illness
• Manifestations of latent diabetes mellitus
• Increased requirements for insulin or oral hypoglycemic agents in diabetics

Ophthalmic

• Posterior subcapsular cataracts
• Glaucoma
• Increased intraocular pressure
• Exophthalmos

Metabolic

• Negative nitrogen balance due to protein catabolism

More resources:

cortisone

Cortisone

Cortisone - Includes detailed dosage instructions.

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