COPD Side Effects

Generic name: dyphylline / guaifenesin

Note: This document contains side effect information about dyphylline / guaifenesin. Some of the dosage forms listed on this page may not apply to the brand name COPD.

Some side effects of COPD may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to dyphylline / guaifenesin: oral liquid, oral syrup, oral tablet

Get emergency medical help if you have any of these signs of an allergic reaction while taking dyphylline / guaifenesin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

• fast, pounding, or uneven heartbeats;

• rapid breathing;

• muscle twitching;

• feeling like you might pass out;

• seizure (convulsions); or

• extreme thirst with headache, nausea, vomiting, and weakness.

Less serious side effects of dyphylline / guaifenesin may include:

• headache;

• mild nausea, vomiting, or stomach pain;

• feeling restless, agitated, or irritable;

• sleep problems (insomnia); or

• warmth, redness, or tingly feeling under your skin.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to dyphylline / guaifenesin: oral capsule, oral liquid, oral syrup, oral tablet

Cardiovascular

Cardiovascular side effects have included palpitations, tachycardia, extrasystoles, flushing, hypotension, circulatory failure, and ventricular arrhythmias.

Endocrine

Endocrine side effects have included hyperglycemia and inappropriate ADH syndrome.

Gastrointestinal

Gastrointestinal side effects have included nausea, vomiting, epigastric pain, hematemesis and diarrhea.

Nervous system

Nervous system side effects have included headache, irritability, restlessness, insomnia, hyperexcitability, agitation, muscle twitching, and generalized clonic and tonic convulsions.

Renal

Renal side effects have included albuminuria, diuresis and both gross and microscopic hematuria.

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