Codeine / phenylephrine Side Effects
Not all side effects for codeine / phenylephrine may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to codeine / phenylephrine: liquid
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur while taking codeine / phenylephrine:
Constipation; diarrhea; dizziness; drowsiness; excitability; headache; nausea; nervousness or anxiety; stomach pain; trouble sleeping.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; confusion; difficulty urinating; fast, slow, or irregular heartbeat; hallucinations; loss of coordination; mental or mood changes; numbness or tingling of the skin; persistent loss of appetite; persistent trouble sleeping; ringing in the ears; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; shortness of breath; tremor; wheezing.
For Healthcare Professionals
Applies to codeine / phenylephrine: oral liquid
Nervous system side effects have included sedation, dizziness, sleepiness, disturbed coordination, fatigue, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, euphoria, paresthesias, vertigo, hysteria, neuritis, tinnitus, acute labyrinthitis, and convulsions.[Ref]
Ocular side effects have included blurred vision and diplopia.[Ref]
Gastrointestinal side effects have included epigastric distress, anorexia, nausea, vomiting, diarrhea, and constipation.[Ref]
Genitourinary side effects have included urinary frequency, difficult urination, urinary retention, and early menses.[Ref]
Respiratory side effects have included thickening of bronchial secretions, tightness of chest, wheezing, dryness of mouth, nose and throat, and nasal stuffiness.[Ref]
Dermatologic side effects have included urticaria, drug rash, photosensitivity, and pruritis.[Ref]
Hypersensitivity side effects have included anaphylactic shock.[Ref]
Cardiovascular side effects have included hypotension, palpitations, tachycardia, and extra systoles.[Ref]
Hematologic side effects have included hemolytic anemia, thrombocytopenia, and agranulocytosis.[Ref]
1. "Product Information. Ala-Hist AC (codeine-phenylephrine)." Poly Pharmaceuticals Inc, Quitman, MS.
More about codeine/phenylephrine
Related treatment guides
Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.