Clevidipine Side Effects

Some side effects of clevidipine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to clevidipine: intravenous emulsion

Get emergency medical help if you have any of these signs of an allergic reaction while taking clevidipine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregiver at once if you have a serious side effect such as:

• feeling like you might pass out;

• rapid heart rate;

• urinating less than usual or not at all;

• weakness, confusion, increased thirst, loss of appetite, vomiting, pounding heartbeats or fluttering in your chest;

• swelling, weight gain, feeling short of breath;

• vomiting, diarrhea, stomach cramps, bloating, severe constipation;

• chest pain or heavy feeling, pain spreading to the arm or shoulder, sweating, general ill feeling;

• slow heart rate, weak pulse, fainting, slow breathing (breathing may stop); or

• dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, uneven heartbeats, seizure).

Less serious side effects of clevidipine may include:

• mild headache;

• mild nausea; or

• mild constipation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to clevidipine: intravenous emulsion

Cardiovascular

Cardiovascular side effects have included atrial fibrillation (up to 21%), myocardial infarction (less than 1%), cardiac arrest (less than 1%), systemic hypotension, and reflex tachycardia. Hypotension and reflex tachycardia have been reported during postmarketing experience.

Gastrointestinal

Gastrointestinal side effects have included nausea (up to 21%) and vomiting (3.2%). Ileus and nausea have been reported during postmarketing experience.

Renal

Renal side effects have included acute renal failure (up to 9%).

Nervous system

Nervous system side effects have included headache (6.3%) and syncope (less than 1%).

Respiratory

Respiratory side effects have included dyspnea (less than 1%).

Other

Other side effects have included decreased oxygen saturation (possible pulmonary shunting) during postmarketing experience.

Metabolic

Metabolic side effects have included increased blood triglycerides during postmarketing experience.

Hypersensitivity

Hypersensitivity side effects have included hypersensitivity during postmarketing experience.

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