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Chlorzoxazone Side Effects

Brand Names: Parafon Forte DSC

Please note - some side effects for Chlorzoxazone may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects of Chlorzoxazone - for the Consumer

Chlorzoxazone

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Chlorzoxazone:

Dizziness; drowsiness; general body discomfort; light-headedness; nausea; nervousness; over-stimulation.

Seek medical attention right away if any of these SEVERE side effects occur when using Chlorzoxazone:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); black, tarry stools; bloody or coffee ground-like vomit; fever; symptoms of liver problems (eg, loss of appetite; unusual nausea, vomiting, or tiredness; stomach pain; dark urine; pale stools; yellowing of the skin or eyes); weight loss.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

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Chlorzoxazone Side Effects - for the Professional

Chlorzoxazone

Chlorzoxazone containing products are usually well tolerated. It is possible in rare instances that Chlorzoxazone may have been associated with gastrointestinal bleeding. Drowsiness, dizziness, lightheadedness, malaise, or over-stimulation may be noted by an occasional patient. Rarely, allergic-type skin rashes, petechiae, or ecchymoses may develop during treatment. Angioneurotic edema or anaphylactic reactions are extremely rare. There is no evidence that the drug will cause renal damage. Rarely, a patient may note discoloration of the urine resulting from a phenolic metabolite of Chlorzoxazone. This finding is of no known clinical significance.  

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Side Effects by Body System - for Healthcare Professionals

Gastrointestinal

Gastrointestinal side effects of chlorzoxazone have rarely included gastrointestinal bleeding.

Nervous system

Nervous system side effects have included drowsiness, dizziness, light-headedness, malaise, and overstimulation.

Hypersensitivity

Hypersensitivity side effects have rarely included skin rashes, petechiae, angioneurotic edema, anaphylactic reactions, and ecchymoses.

Renal

Renal side effects attributed to a phenolic metabolite have rarely included urine discoloration.

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