Chlorpheniramine/Dihydrocodeine/Phenylephrine Side Effects

Brand Names: Pancof-PD, Novahistine DH

Please note - some side effects for Chlorpheniramine/Dihydrocodeine/Phenylephrine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Chlorpheniramine/Dihydrocodeine/Phenylephrine - for the Consumer

Chlorpheniramine/Dihydrocodeine/Phenylephrine Liquid

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Chlorpheniramine/Dihydrocodeine/Phenylephrine Liquid:

Constipation; dizziness; drowsiness; dry mouth, throat, or nose; excitement; nausea; stomach upset; thickening or mucus in nose or throat.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; flushing or redness of face.

Side Effects by Body System

General

General side effects including light-headedness, dizziness, drowsiness, headache, fatigue, and sedation have been among the most frequently reported with opioid use. Confusion, abdominal pain, lassitude, giddiness, increased irritability or excitement (especially in children) have been reported. Hallucinations, severe narcosis, and vivid dreams have been reported rarely.

Gastrointestinal

Gastrointestinal side effects including nausea, vomiting, and constipation have been among the most frequently reported with opioid use. Diarrhea, dry mouth, indigestion, anorexia, spasm of biliary tract have been reported.

Dermatologic

Dermatologic side effects including sweating, pruritus, and skin reactions have been among the most frequently reported with opioid use. Flushing has been reported.

Other

Symptoms of dihydrocodeine withdrawal consist of irritability, restlessness, insomnia, diaphoresis, anxiety, and palpitations.

Other side effects of dihydrocodeine have included psychological dependence, physical dependence, and tolerance have been reported to develop upon repeated administration.

Renal

Renal side effects including granulomatous interstitial nephritis and acute renal failure have been reported rarely during dihydrocodeine administration.

Cardiovascular

Cardiovascular side effects including orthostatic hypotension and cardiac palpitations have been reported.

Respiratory

Respiratory side effects including respiratory depression have been reported.

Ocular

Ocular side effects including miosis and blurred vision have been reported.

Genitourinary

Genitourinary side effects including urinary retention have been reported.

Hypersensitivity

Hypersensitivity side effects including anaphylactoid reactions have been reported rarely.

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