Chlordiazepoxide and clidinium Side Effects

Please note - some side effects for Chlordiazepoxide and clidinium may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects by Body System

Nervous system

The elderly and debilitated may be more susceptible to the side effects of chlordiazepoxide-clidinium. Drowsiness, ataxia, and confusion have occasionally been reported at the lower dosage ranges.

Nervous system side effects have included drowsiness, ataxia, confusion, and extrapyramidal symptoms. Chlordiazepoxide-clidinium may impair the psychomotor skills necessary for driving. Changes in electroencephalogram (EEG) patterns (low-voltage fast activity) have been reported during and after chlordiazepoxide treatment.

Gastrointestinal

Gastrointestinal side effects have included nausea, constipation, and dryness of the mouth.

Hematologic

Hematologic side effects have included blood dyscrasias (including agranulocytosis).

Hepatic

Hepatic side effects have included jaundice and hepatic dysfunction.

Other

Withdrawal symptoms after abrupt cessation of chlordiazepoxide-clidinium may include dysphoria, insomnia, convulsions, tremor, abdominal and muscle cramps, vomiting, sweating, agitation, restlessness, and anxiety.

Other side effects have included increased and decreased libido, edema, and withdrawal symptoms. Rarely, syncope has been reported.

Ocular

Ocular side effects have included blurring of vision.

Genitourinary

Genitourinary side effects have included minor menstrual irregularities and urinary hesitancy.

Dermatologic

Dermatologic side effects have included skin eruptions.

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