Caltrate Side Effects
Generic Name: calcium carbonate
Note: This page contains information about the side effects of calcium carbonate. Some of the dosage forms included on this document may not apply to the brand name Caltrate.
Not all side effects for Caltrate may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to calcium carbonate: chewable tablets
Other dosage forms:
No COMMON side effects have been reported with this medicine. Seek medical attention right away if any of these SEVERE side effects occur while taking calcium carbonate (the active ingredient contained in Caltrate)
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).
For Healthcare Professionals
Applies to calcium carbonate: compounding powder, oral capsule, oral gum, oral powder, oral suspension, oral tablet, oral tablet chewable
Rebound hyperacidity has been associated with calcium salt antacids. This side effect does not appear to be due to the acid buffering capacity of calcium carbonate (the active ingredient contained in Caltrate) but is a consequence of a specific action of calcium on the parietal cell.
Rare cases of calcium carbonate gallstones have been reported in the pediatric literature.
Gastrointestinal side effects have included rebound hyperacidity, constipation (6% to 37%) and gallstones (rarely).
Prolonged ingestion of large amounts of calcium carbonate (the active ingredient contained in Caltrate) and other sources of exogenous calcium can rarely result in the "milk alkali syndrome" and calcinosis. The milk alkali syndrome is characterized by the triad of hypercalcemia, metabolic alkalosis, and renal insufficiency.
Metabolic side effects have rarely included hypercalcemia and hypophosphatemia. Hypercalcemia may be more likely and more severe in patients with renal dysfunction. In patients on chronic dialysis, hypercalcemia may also result from excessive calcium in the dialysate, vitamin D intoxication, or severe secondary hyperparathyroidism. Other metabolic side effects have rarely included "mild alkali syndrome", calcinosis, and irreversible renal damage.
Renal side effects have included renal failure, formation of renal calcium and a single case report of a calcium carbonate (the active ingredient contained in Caltrate) and calcium phosphate-filled renal cyst.
The renal failure that accompanies hypercalcemia and alkalosis in the milk alkali syndrome is usually transient.
More about Caltrate (calcium carbonate)
- Other brands: Tums Regular Strength, Tums Extra Strength 750, Tums Ultra 1000, Maalox Regular Strength, More (28) »
Related treatment guides
Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.