Calciferol Side Effects

Generic Name: ergocalciferol

Note: This page contains information about the side effects of ergocalciferol. Some of the dosage forms included on this document may not apply to the brand name Calciferol.

Not all side effects for Calciferol may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to ergocalciferol: oral capsules and solution

Side effects include:

Possible hypervitaminosis D effects: polyuria, nocturia, polydipsia, hypercalciuria, reversible azotemia, hypertension, nephrocalcinosis, generalized vascular calcification, irreversible renal insufficiency (may be fatal), mental retardation, widespread soft tissue calcification, osteoporosis, dwarfism, vague aches, stiffness, weakness, nausea, anorexia, constipation, mild acidosis, anemia, weight loss.

For Healthcare Professionals

Applies to ergocalciferol: compounding powder, injectable solution, oral capsule, oral solution, oral tablet

Metabolic

Metabolic side effects have included hypercalcemia.[Ref]

Hypercalciuria may precede hypercalcemia in patients being treated with ergocalciferol. Early signs and symptoms of hypercalcemia include headache, anorexia, nausea, vomiting, gastrointestinal disturbances, abdominal cramps, dry mouth, metallic taste, weakness, fatigue, muscle and bone pain, ataxia, tinnitus, and vertigo. Later stages of hypercalcemia may present as pruritus, mental confusion, hypertension, cardiac arrhythmias, seizures, metastatic calcification, and renal insufficiency (manifested as polyuria, nocturia, polydipsia, and proteinuria).[Ref]

References

1. Araugo OE, Flowers FP, Brown K "Vitamin D therapy in psoriasis." DICP 25 (1991): 835-9

2. Miller SM "New perspectives on vitamin D." Am J Med Technol 49 (1983): 27-37

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