C/Rose Hips Side Effects
Generic Name: acerola
Please note - some side effects for C/Rose Hips may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
Side Effects by Body System
Renal
Renal side effects have included oxalate and urate kidney stones.
Hyperoxaluria appears to be dose-related.
Nervous system
Nervous system side effects have included dizziness, faintness, fatigue, and headache in less than 1% of patients. Migraine headache has also been reported.
Migraine headache has been reported with a daily dose of 6 grams.
The manufacturer reports temporary dizziness and faintness may be associated with too rapid of a rate during intravenous administration.
Other
Conditional scurvy is reported to occur following excessive doses of ascorbic acid over a prolonged period of time. The mechanism of action for this condition is thought to be that large doses of ascorbic acid condition the patient over time for rapid clearance of ascorbic acid resulting in scurvy. The plasma levels of ascorbic acid appear to remain within normal limits. The actual existence of conditional scurvy remains controversial.
Other side effects have included flank pain in less than 1% of patients. Conditional scurvy has also been reported.
Gastrointestinal
Nausea, diarrhea, and abdominal cramps appears to be associated with doses exceeding 2 g per day, although there have been some reports with as little as 1 g per day.
Esophagitis appears to be associated with prolonged or increased contact of ascorbic acid tablets with the esophageal mucosa.
Gastrointestinal side effects have included nausea, diarrhea, abdominal cramps, and esophagitis.
Hematologic
Hematologic side effects have included hemolysis.
The majority of hemolysis reports have been associated with patients who have concurrent glucose-6-phosphate dehydrogenase deficiency.
Local
Local side effects have included transient mild soreness at the site of injection.
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