Buspirone Side Effects
Not all side effects for buspirone may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to buspirone: oral tablet
In addition to its needed effects, some unwanted effects may be caused by buspirone. In the event that any of these side effects do occur, they may require medical attention.
You should check with your doctor immediately if any of these side effects occur when taking buspirone:Rare
- Chest pain
- fast or pounding heartbeat
- mental depression
- muscle weakness
- numbness, tingling, pain, or weakness in the hands or feet
- skin rash or hives
- sore throat
- stiffness of the arms or legs
- uncontrolled movements of the body
If any of the following symptoms of overdose occur while taking buspirone, get emergency help immediately:Symptoms of overdose
- Dizziness or lightheadedness especially when getting up from a sitting or lying position suddenly
- drowsiness (severe)
- loss of consciousness
- nausea or vomiting
- stomach upset
- very small pupils of the eyes
Some of the side effects that can occur with buspirone may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common
- Restlessness, nervousness, or unusual excitement
- Blurred vision
- clamminess or sweating
- decreased concentration
- dryness of the mouth
- muscle pain, spasms, cramps, or stiffness
- ringing in the ears
- trouble with sleeping, nightmares, or vivid dreams
- unusual tiredness or weakness
For Healthcare Professionals
Applies to buspirone: compounding powder, oral tablet
There is currently no evidence for withdrawal, dependence or rebound anxiety after discontinuation of buspirone.
Nervous system side effects have occurred and include dizziness, drowsiness and headache in about 10% of patients. Movement disorders such as myoclonus, oral dyskinesia, dystonia, and akathisia have been reported rarely. Extrapyramidal side effects, cogwheel rigidity, ataxia, emotional lability, serotonin syndrome, recall difficulty, parkinsonism, restlessness, and restless leg syndrome have been reported in postmarketing experience.
Gastrointestinal side effects including nausea have occurred in up to 11% of patients. Constipation, diarrhea and vomiting have also been reported.
Psychiatric side effects including mania, hypomania, vivid dreams, delirium, panic attack, and psychosis have been reported rarely. Dysphoria has been reported with long-term administration.
Genitourinary side effects such as priapism and urinary retention have been reported rarely.
Cardiovascular side effects following acute administration of buspirone have included transient, non-pathologic changes in blood pressure in male psychiatric patients. Effects on blood pressure (either increases or decreases) appear to be associated with the diagnosis.
Endocrine side effects have included elevations in plasma prolactin and cortisol.
An increase in appetite in some patients has been reported.
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