Brimonidine and timolol ophthalmic Side Effects
Please note - some side effects for Brimonidine and timolol ophthalmic may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
Side Effects by Body System - for Healthcare Professionals
Applies to: ophthalmic solution
Ocular side effects have included allergic conjunctivitis, follicular conjunctivitis, conjunctival hyperemia, eye pruritis, ocular burning, and stinging. Also reported were diplopia, choroidal detachment following filtration surgery, cystoid macular edema, decreased corneal sensitivity, pseudophemphigoid ptosis, refractive changes, blepharitis, blepharoconjunctivitis, conjunctival edema, conjunctival hemorrhage, conjunctivitis, blurred vision, corneal erosion, epiphora, eye discharge, eye dryness, eye irritation, eye pain, eyelid edema, eyelid pruritis, lid disorder, tearing, visual field defect, vitreous detachment, vitreous disorder, vitreous floaters, worsened visual acuity, iritis, keratoconjunctivitis sicca, miosis, foreign body sensation, superficial punctate keratitis, and visual disturbance.
Cardiovascular side effects have included arrythmia, bradycardia, tachycardia, cardiac arrest, cardiac failure, cerebral ischemia, cerebral vascular accident, claudication, cold hands and feet, edema, heart block, palpitation, pulmonary edema, Raynaud's phenomena, syncope, and worsening of angina pectoris.
Gastrointestinal side effects have included anorexia, diarrhea, gastrointestinal pain, gastrointestinal disorder, dyspepsia, hepatomegaly, ischemic colitis, mesenteric arterial thrombosis, diarrhea, vomiting, and nausea.
Immunologic side effects have included systemic lupus erythematosus.
Nervous system side effects have included increased signs and symptoms of myasthenia gravis, insomnia, nightmares, paresthesias, headache, asthenia, somnolence, dizziness, fatigue, photophobia, taste perversion, confusion, slightly clouded sensorium, and vertigo
Psychiatric side effects have included hallucinations, anxiety, disorientation, nervousness, memory loss, behavorial changes and psychic disturbances, slightly clouded sensorium, decreased performance on neuropsychometrics, diminished concentration, emotional liability, an acute reversible syndrome characterized by disorientation for time and place, and reversible mental depression progressing to catatonia.
Respiratory side effects have included cough, oral dryness, dyspnea, bronchitis, bronchial obstruction, rales, bronchospasm, nasal dryness, dyspnea, nasal congestion, rhinitis, sinus infection, sinusitis, pharyngitis, colds, and respiratory infections.
Hematologic side effects have included agranulocytosis, nonthrombocytopenic purpura, and thrombocytopenic purpura,
Genitourinary side effects have included urination difficulties, decreased libido, impotence, Peyronie's disease, and retroperitoneal fibrosis.
Hypersensitivity side effects have included anaphylaxis, angioedema, urticaria, fever combined with aching and sore throat, laryngospasm with respiratory distress, erythematous rash and both generalized and localized rash.
Endocrine side effects have included masking of symptoms of hypoglycemia in diabetic patients, hypercholesterolemia, hyperglycemia, and hypoglycemia.
General side effects have included decreased exercise tolerance, extremity pain, local weakness, weight loss, tinnitus, flu syndrome, and abnormal taste.
Musculoskeletal side effects have included arthralgia.Top
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