Bonine for Kids Side Effects

Generic name: cyclizine

Note: This document contains side effect information about cyclizine. Some of the dosage forms listed on this page may not apply to the brand name Bonine for Kids.

Some side effects of Bonine for Kids may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to cyclizine: oral tablet

Stop taking cyclizine (the active ingredient contained in Bonine for Kids) and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take cyclizine and talk to your doctor if you experience

• drowsiness;

• restlessness, excitation, nervousness, or insomnia;

• blurred vision;

• dry mouth, nose, or throat;

• decreased appetite, nausea, or vomiting;

• difficulty urinating; or

• an irregular or fast heartbeat.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

For Healthcare Professionals

Applies to cyclizine: oral tablet, oral tablet chewable

Nervous system

Nervous system side effects have included drowsiness and sedation in many patients. Motor skills may be impaired. Cyclizine (the active ingredient contained in Bonine for Kids) may also cause restlessness, excitation, nervousness, and insomnia.

Lingual-facial-buccal dyskinesias and generalized chorea occurred in an elderly patient, most probably due to the anticholinergic activity of cyclizine.

Cardiovascular

Cardiovascular side effects have included hypotension, tachycardia, and palpitations. Cardiovascular changes recorded after intravenous administration of cyclizine (the active ingredient contained in Bonine for Kids) have included increase in heart rate, decrease in cardiac output, and increases in right atrial, pulmonary arterial, pulmonary artery wedge, and systemic arterial pressures.

Gastrointestinal

Gastrointestinal side effects have been mild in nature. These have included nausea, dry mouth, and constipation.

Ocular

Ocular side effects have included blurred vision, diplopia, and dry eyes due to its anticholinergic effects.

Genitourinary

Genitourinary side effects have included urinary retention and dysuria.

Hepatic

Hepatic side effects have included a case report of hepatitis in at least one child. This side effect was confirmed upon drug rechallenge.

Hypersensitivity

Hypersensitivity side effects have included fixed drug eruptions.

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