Bisacodyl and polyethylene glycol (PEG) 3350 with electrolytes Side Effects
Please note - some side effects for Bisacodyl and polyethylene glycol (PEG) 3350 with electrolytes may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
Side Effects by Body System - for Healthcare Professionals
Applies to: oral kit
Mallory-Weiss tears are quite rare with administration of PEG-ELS. In one study it occurred in only 0.06% of over 3,000 patients.
Complete rectal prolapse was reported in a 71-year-old who had been given 4 L of PEG-ELS. The patient was observed for 2 days and had no recurrence of the prolapse.
During administration of PEG-ELS (4 liters) two deaths occurred in patients with end-stage renal failure following the development of vomiting, diarrhea and dysnatremia.
Gastrointestinal side effects have been reported the most frequently. These have included nausea (17.1%), cramping (9.1%), abdominal fullness (22.3%), vomiting (5.9%) and overall discomfort (19.1%).
A small percentage of patients who received PEG-ELS have reportedly experienced Mallory-Weiss tears of the esophagus and esophageal perforation. In addition, at least one case of rectal prolapse has been reported.
Dermatologic side effects reported with PEG-ELS have rarely included urticaria and dermatitis.
Cardiovascular side effects of PEG-ELS have included arrhythmias and asystole.
Cardiac arrhythmias, especially increased ventricular ectopy, have been associated with PEG-ELS use.
The manufacturer notes an isolated case of asystole following ingestion of PEG-ELS in a geriatric patient (equal to or greater than 60 years of age).
A 70-year-old male developed shortness of breath, wheezing, skin flushing, and lowered blood pressure after drinking a second glass of PEG-ELS.
Hypersensitivity side effects with PEG-ELS have rarely included anaphylaxis.
Other side effects with PEG-ELS have included rhinorrhea.
Respiratory side effects with PEG-ELS have included sudden dyspnea with pulmonary edema, and 'butterfly-like' infiltrate on chest X-ray.
The manufacturer notes isolated reports of 'butterfly-like' infiltrate on chest X-ray following vomiting and aspiration of PEG-ELS and sudden dyspnea with pulmonary edema in geriatric patients (equal to or greater than 60-years-old).
Tonic-clonic seizures have been reported in patients with and without previous history of seizures following administration of PEG-ELS (4 liters).
Nervous system side effects have included tonic-clonic seizures.Top
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