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Betoptic Side Effects

Generic Name: betaxolol ophthalmic

Note: This page contains information about the side effects of betaxolol ophthalmic. Some of the dosage forms included on this document may not apply to the brand name Betoptic.

Not all side effects for Betoptic may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to betaxolol ophthalmic: ophthalmic solution, ophthalmic suspension

In addition to its needed effects, some unwanted effects may be caused by betaxolol ophthalmic (the active ingredient contained in Betoptic). In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking betaxolol ophthalmic:

More common
  • Pain in the eye
  • Blistering, peeling, or loosening of skin
  • blue lips, fingernails, or skin
  • blurred vision
  • change in color vision
  • chest pain or discomfort
  • chills
  • cough
  • crusting of eyelashes
  • decreased urine output
  • decreased vision
  • diarrhea
  • different size pupils of the eyes
  • difficulty in breathing, chewing, swallowing, or talking
  • difficulty seeing at night
  • dilated neck veins
  • double vision
  • drainage from eyes
  • drooping eyelids
  • extreme fatigue
  • fast, slow, or irregular heartbeat
  • feeling of having something in the eye
  • hives
  • increased sensitivity of eyes to sunlight
  • irregular, fast or slow, or shallow breathing
  • irritation or inflammation of eye
  • itching, dryness of eyes
  • itching skin
  • joint or muscle pain
  • lightheadedness, dizziness, or fainting
  • muscle weakness
  • noisy breathing
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • severe tiredness
  • shortness of breath
  • skin rash
  • sore throat
  • sores, ulcers, or white spots in mouth or on lips
  • sweating
  • swelling of eyelids
  • swelling of face, fingers, feet, or lower legs
  • tearing
  • thickened mucous from lungs
  • tightness in chest
  • troubled breathing
  • unusual tiredness or weakness
  • weight gain
  • wheezing

Some of the side effects that can occur with betaxolol ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

  • Bad, unusual, or unpleasant (after) taste
  • change in sense of smell
  • change in taste
  • discouragement
  • feeling of constant movement of self or surroundings
  • feeling sad or empty
  • hair loss
  • headaches
  • irritability
  • lack of appetite
  • loss of interest or pleasure
  • redness, swelling, or soreness of tongue
  • sensation of spinning
  • sleeplessness
  • tiredness
  • trouble concentrating
  • trouble sleeping
  • unable to sleep
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

For Healthcare Professionals

Applies to betaxolol ophthalmic: ophthalmic solution, ophthalmic suspension


The most commonly reported side effect was eye discomfort.[Ref]


Very common (10% or more): Eye discomfort (16%)
Common (1% to 10%): Foreign body sensation in eyes
Uncommon (0.1% to 1%): Tearing on instillation of the drops, punctate keratitis, asthenopia, eye discharge, eyelid margin crusting, conjunctival disorder, conjunctival edema, ocular hyperemia
Rare (less than 0.1%): Signs and symptoms of ocular irritation (e.g., burning, stinging, itching, tearing, redness), pain, corneal punctuate staining, decreased corneal sensitivity, dry eyes, blepharitis, keratitis, blurred vision, anisocoria, photophobia, blepharoconjunctivitis, cataract, refraction disorder
Frequency not reported: Choroidal detachment following filtration surgery, corneal erosion, ptosis, diplopia[Ref]


Rare (less than 0.1%): Systemic allergic reactions including angioedema, urticaria, localized and generalized rash, pruritus, anaphylactic reaction[Ref]


Rare (less than 0.1%): Bradycardia, atrioventricular block, cardiac failure, hypotension, Raynaud's phenomenon, cold hands and feet, exacerbation of intermittent claudication
Frequency not reported: Congestive heart failure, chest pain, palpitations, edema, arrhythmia, cardiac arrest[Ref]


Uncommon (0.1% to 1%): Rhinitis
Rare (less than 0.1%): Bronchospasm (predominantly in patients with pre-existing bronchospastic disease), dyspnea, asthma, rhinorrhea
Frequency not reported: Cough, thickened bronchial secretions, respiratory failure, antral lavage[Ref]


Rare (less than 0.1%): Insomnia, sleep disorders, depression, hallucinations, psychoses, confusion, nightmares[Ref]

Nervous system

Rare (less than 0.1%): Dizziness, paresthesia, headache
Frequency not reported: Memory loss, syncope, cerebrovascular accident, cerebral ischemia, increases in signs and symptoms of myasthenia gravis, dysgeusia, vertigo, lethargy[Ref]


Rare (less than 0.1%): Nausea, vomiting, diarrhea
Frequency not reported: Dyspepsia, dry mouth, abdominal pain, glossitis[Ref]


Rare (less than 0.1%): Alopecia, skin rash
Frequency not reported: Psoriasiform rash or exacerbation of psoriasis, hives, toxic epidermal necrolysis, hair loss, periorbital edema[Ref]


Rare (less than 0.1%): Masking of the symptoms of thyrotoxicosis[Ref]


Rare (less than 0.1%): Sexual dysfunction
Frequency not reported: Decreased libido[Ref]


Rare (less than 0.1%): Increase in anti-nuclear antibodies (ANA)[Ref]


Rare (less than 0.1%): Hypoglycemia[Ref]


Frequency not reported: Myalgia[Ref]


Frequency not reported: Asthenia[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. "Product Information. Betoptic (betaxolol ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.

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