Benicar Side Effects
Generic name: olmesartan
Note: This document contains side effect information about olmesartan. Some of the dosage forms listed on this page may not apply to the brand name Benicar.
Some side effects of Benicar may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to olmesartan: oral tablet
Along with its needed effects, olmesartan (the active ingredient contained in Benicar) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking olmesartan:Less common
- Blood in the urine
- body aches or pain
- cough or cough producing mucus
- difficulty with breathing
- ear congestion
- loss of voice
- nasal congestion
- runny nose
- sore throat
- tightness in the chest
- unusual tiredness or weakness
- Bladder pain
- bloating or swelling of the face, arms, hands, lower legs, or feet
- chest pain
- cloudy urine
- difficult, burning, or painful urination
- fast, pounding, or irregular heartbeat or pulse
- frequent urge to urinate
- joint pain, stiffness, or swelling
- lower back, side, or stomach pain
- swelling of the feet or lower legs
- dark-colored urine
- diarrhea (severe) with weight loss
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- muscle cramps or spasms
- muscle pain or stiffness
- nausea or vomiting
- weakness or heaviness of the legs
Get emergency help immediately if any of the following symptoms of overdose occur while taking olmesartan:Symptoms of overdose
- Blurred vision
- chest pain or discomfort
- dizziness, faintness, or lightheadedness
Some side effects of olmesartan may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less common
- Back pain
- dry mouth
- flushed, dry skin
- fruit-like breath odor
- general feeling of discomfort or illness
- increased hunger
- increased thirst
- increased urination
- loss of appetite
- muscle aches
- pain or tenderness around the eyes and cheekbones
- tender, swollen glands in the neck
- trouble sleeping
- trouble swallowing
- unexplained weight loss
- Acid or sour stomach
- difficulty with moving
- feeling of constant movement of self or surroundings
- rapid weight gain
- sensation of spinning
- tingling of the hands or feet
- unusual weight gain or loss
- Hair loss or thinning of the hair
- lack or loss of strength
- redness of the skin
For Healthcare Professionals
Applies to olmesartan: oral tablet
Nervous system side effects have included dizziness (3% vs. 1% with placebo), vertigo (0.5% to 1% with placebo), and insomnia (0.5% to 1% with placebo). Asthenia has been reported in postmarketing experience.
Respiratory side effects have included cough (0.9% vs. 0.7% with placebo), bronchitis, rhinitis, pharyngitis, sinusitis, and upper respiratory tract infection.
Gastrointestinal side effects including abdominal pain, dyspepsia, gastroenteritis, and nausea have been reported in 0.5% to 1% of patients. Vomiting has been reported in postmarketing experience. Diarrhea has been reported in more than 1% of patients but at the same or greater incidence than placebo.
Cardiovascular side effects including tachycardia, chest pain, and peripheral edema have been reported in 0.5% to 1% of patients. At least 5 cases of facial edema and at least one case of olmesartan-induced angioedema, which resolved over 7 to 10 days after discontinuing olmesartan (the active ingredient contained in Benicar) have been reported.
Metabolic side effects have included hyperglycemia and hypertriglyceridemia. Hyperkalemia has been reported in postmarketing experience.
Musculoskeletal side effects including arthralgia, arthritis, myalgia, and skeletal pain have been reported in 0.5% to 1% of patients. Rhabdomyolysis have been reported during postmarketing experience in patients receiving angiotensin II receptor blockers.
Dermatologic side effects have included rash (0.5% to 1%), alopecia, pruritus, and urticaria.
Genitourinary side effects including urinary tract infection have been reported in 0.5% to 1% of patients. Hematuria has been reported in more than 1% of patients but at the same or greater incidence than placebo.
Hematologic side effects have included decreased hemoglobin and hematocrit.
Hepatic side effects have rarely included liver enzyme and serum bilirubin elevations.
Other side effects including back pain, increased creatine phosphokinase, headache, inflicted injury, influenza-like symptoms, and have been reported in more than 1% of patients but at the same or greater incidence than placebo. Fatigue and pain have been reported in 0.5% to 1% of patients.
Renal side effects associated with ACE inhibitors have included increases in serum creatinine or BUN in patients with renal artery stenosis. Acute renal failure and increased serum creatinine levels have been reported in postmarketing experience.
Hypersensitivity side effects including rare cases of angioedema and anaphylactic reactions have been reported in patients receiving olmesartan (the active ingredient contained in Benicar)
More Benicar resources
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