Bactroban Cream Side Effects
Please note - some side effects for Bactroban Cream may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
Bactroban Cream Side Effects - for the Professional
Bactroban Cream
In 2 randomized, double-blind, double-dummy trials, 339 patients were treated with topical Bactroban Cream plus oral placebo. Adverse events thought to be possibly or probably drug-related occurred in 28 (8.3%) patients. The incidence of those events that were reported in at least 1% of patients enrolled in these trials were: Headache (1.7%), rash, and nausea (1.1% each).
Other adverse events thought to be possibly or probably drug-related which occurred in less than 1% of patients were: Abdominal pain, burning at application site, cellulitis, dermatitis, dizziness, pruritus, secondary wound infection, and ulcerative stomatitis.
In a supportive study in the treatment of secondarily infected eczema, 82 patients were treated with Bactroban Cream. The incidence of adverse events thought to be possibly or probably drug-related was as follows: Nausea (4.9%), headache, and burning at application site (3.6% each), pruritus (2.4%) and 1 report each of abdominal pain, bleeding secondary to eczema, pain secondary to eczema, hives, dry skin, and rash.
TopSide Effects by Body System - for Healthcare Professionals
Local
Local adverse effects may be associated with mupirocin application. Mupirocin ointment or cream may commonly cause itching, pain, stinging, and burning. Local effects from the nasal formulation have included epistaxis, rhinitis, taste perversion, pharyngitis, burning, and cough.
Mupirocin ointment in a polyethylene glycol base has previously (prior to the release of a nasal formulation) been used intranasally. Common side effects associated with such use, which may be related to the polyethylene glycol, include nasal congestion, dryness, burning or irritation and unpleasant taste.
Gastrointestinal
Gastrointestinal side effects have included nausea (1.1%), abdominal pain (<1%), and diarrhea (<1%). Dry mouth has been reported with mupirocin nasal (<1%).
Hypersensitivity
Hypersensitivity reactions have infrequently included allergic contact dermatitis.
Nervous system
Nervous system side effects associated with intranasal mupirocin have included headache (9%). Dizziness has been reported with mupirocin ointment (<1%).
Ocular
Ocular side effects associated with mupirocin nasal ointment have included blepharitis (<1%).
Dermatologic
Dermatologic side effects associated with mupirocin ointment or cream have included pain and bleeding secondary to eczema, cellulitis, dermatitis, increased exudate, secondary wound infection, hives, and rash.
TopDisclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
