Bacampicillin Side Effects

Please note - some side effects for Bacampicillin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects by Body System - for Healthcare Professionals

Hypersensitivity

Besides the urticarial rash of hypersensitivity to bacampicillin, a delayed hypersensitivity maculopapular rash may occur 10 to 12 days after bacampicillin therapy is begun.

Hypersensitivity reactions have included rare cases of interstitial nephritis, Henoch-Schonlein Purpura, focal glomerulonephritis and Stevens-Johnson syndrome.

Hypersensitivity reactions occur in up to 5% of patients treated with bacampicillin. Such reactions may include urticarial rashes, edema, hypotension, fever, eosinophilia, Stevens-Johnson syndrome, and dyspnea. Anaphylaxis is rare. Bacampicillin should not be given to patients with a penicillin allergy.

Gastrointestinal

Gastrointestinal adverse effects occur in 2% to 5% of treated patients and may include diarrhea, nausea, vomiting, and abdominal cramps. Rare cases of hepatitis and pancreatitis have been reported with ampicillin, the active form of bacampicillin. Monitoring of liver function tests is recommended in patients with liver dysfunction.

Bacampicillin-associated diarrhea is usually self-limited and is likely related to alterations in the intestinal microflora. Such alterations may predispose patients to the development of diarrhea from Clostridium difficile toxin. Rare cases of transiently increased liver function tests and chronic cholestasis associated with ampicillin have been reported.

Acute pancreatitis associated with ampicillin has been reported and confirmed by rechallenge with ampicillin in a patient with no other obvious cause of pancreatitis.

Hematologic

Rare cases of thrombocytopenia, leukopenia, red cell aplasia, and anemia have been reported.

Hematologic adverse effects of bacampicillin are rare and include thrombocytopenia, red cell aplasia, and anemia.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.