Ascorbic acid Side Effects
Brand Names: Ascot, Cecon, Cenolate, Cevi-Bid
Please note - some side effects for Ascorbic acid may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
Side Effects of Ascorbic acid - for the Consumer
Ascorbic Acid
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ascorbic Acid:
Seek medical attention right away if any of these SEVERE side effects occur when using Ascorbic Acid:Burning, stinging, or swelling at the injection site.
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
Ascorbic Acid Chewable Tablets
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ascorbic Acid Chewable Tablets:
Seek medical attention right away if any of these SEVERE side effects occur when using Ascorbic Acid Chewable Tablets:Diarrhea; nausea; upset stomach; vomiting.
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); kidney stones (eg, abdominal pain/back pain, painful urination).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
Ascorbic Acid Controlled-Release Capsules
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ascorbic Acid Controlled-Release Capsules:
Seek medical attention right away if any of these SEVERE side effects occur when using Ascorbic Acid Controlled-Release Capsules:Diarrhea; nausea; upset stomach; vomiting.
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); kidney stones (eg, abdominal pain/back pain, painful urination).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
Ascorbic Acid Lozenges
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ascorbic Acid Lozenges:
Seek medical attention right away if any of these SEVERE side effects occur when using Ascorbic Acid Lozenges:Diarrhea; nausea; upset stomach; vomiting.
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); kidney stones (eg, abdominal pain/back pain, painful urination).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
Ascorbic Acid Solution
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ascorbic Acid Solution:
Seek medical attention right away if any of these SEVERE side effects occur when using Ascorbic Acid Solution:Diarrhea; nausea; upset stomach; vomiting.
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); kidney stones (eg, abdominal pain/back pain, painful urination).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
Ascorbic Acid Tablets
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ascorbic Acid Tablets:
Seek medical attention right away if any of these SEVERE side effects occur when using Ascorbic Acid Tablets:Diarrhea; nausea; upset stomach; vomiting.
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); kidney stones (eg, abdominal pain/back pain, painful urination).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
TopSide Effects by Body System - for Healthcare Professionals
Renal
Renal side effects have included oxalate and urate kidney stones.
Hyperoxaluria appears to be dose-related.
Nervous system
Migraine headache has been reported with a daily dose of 6 grams.
The manufacturer reports temporary dizziness and faintness may be associated with too rapid of a rate during intravenous administration.
Nervous system side effects have included dizziness, faintness, fatigue, and headache in less than 1% of patients. Migraine headache has also been reported.
Other
Other side effects have included flank pain in less than 1% of patients. Conditional scurvy has also been reported.
Conditional scurvy is reported to occur following excessive doses of ascorbic acid over a prolonged period of time. The mechanism of action for this condition is thought to be that large doses of ascorbic acid condition the patient over time for rapid clearance of ascorbic acid resulting in scurvy. The plasma levels of ascorbic acid appear to remain within normal limits. The actual existence of conditional scurvy remains controversial.
Gastrointestinal
Nausea, diarrhea, and abdominal cramps appears to be associated with doses exceeding 2 g per day, although there have been some reports with as little as 1 g per day.
Esophagitis appears to be associated with prolonged or increased contact of ascorbic acid tablets with the esophageal mucosa.
Gastrointestinal side effects have included nausea, diarrhea, abdominal cramps, and esophagitis.
Hematologic
Hematologic side effects have included hemolysis.
The majority of hemolysis reports have been associated with patients who have concurrent glucose-6-phosphate dehydrogenase deficiency.
Local
Local side effects have included transient mild soreness at the site of injection.
TopMore Ascorbic acid resources
- ascorbic acid Concise Consumer Information (Cerner Multum)
- ascorbic acid Advanced Consumer (Micromedex) - Includes Dosage Information
- Ascorbic Acid MedFacts Consumer Leaflet (Wolters Kluwer)
- Ascorbic Acid Monograph (AHFS DI)
- Acerola Natural MedFacts for Consumers (Wolters Kluwer)
- Acerola Natural MedFacts for Professionals (Wolters Kluwer)
- Ascot Concise Consumer Information (Cerner Multum)
- Cecon Solution MedFacts Consumer Leaflet (Wolters Kluwer)
- Cenolate Injection MedFacts Consumer Leaflet (Wolters Kluwer)
- Cevi-Bid Controlled-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)
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