Ascorbic acid Side Effects

Brand Names: Ascot, Cecon, Cenolate, Cevi-Bid

Please note - some side effects for Ascorbic acid may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects of Ascorbic acid - for the Consumer

Ascorbic Acid

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ascorbic Acid:

Burning, stinging, or swelling at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur when using Ascorbic Acid:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Ascorbic Acid Chewable Tablets

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ascorbic Acid Chewable Tablets:

Diarrhea; nausea; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur when using Ascorbic Acid Chewable Tablets:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); kidney stones (eg, abdominal pain/back pain, painful urination).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Ascorbic Acid Controlled-Release Capsules

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ascorbic Acid Controlled-Release Capsules:

Diarrhea; nausea; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur when using Ascorbic Acid Controlled-Release Capsules:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); kidney stones (eg, abdominal pain/back pain, painful urination).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Ascorbic Acid Lozenges

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ascorbic Acid Lozenges:

Diarrhea; nausea; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur when using Ascorbic Acid Lozenges:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); kidney stones (eg, abdominal pain/back pain, painful urination).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Ascorbic Acid Solution

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ascorbic Acid Solution:

Diarrhea; nausea; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur when using Ascorbic Acid Solution:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); kidney stones (eg, abdominal pain/back pain, painful urination).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Ascorbic Acid Tablets

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ascorbic Acid Tablets:

Diarrhea; nausea; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur when using Ascorbic Acid Tablets:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); kidney stones (eg, abdominal pain/back pain, painful urination).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

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Side Effects by Body System - for Healthcare Professionals

Renal

Renal side effects have included oxalate and urate kidney stones.

Hyperoxaluria appears to be dose-related.

Nervous system

Migraine headache has been reported with a daily dose of 6 grams.

The manufacturer reports temporary dizziness and faintness may be associated with too rapid of a rate during intravenous administration.

Nervous system side effects have included dizziness, faintness, fatigue, and headache in less than 1% of patients. Migraine headache has also been reported.

Other

Other side effects have included flank pain in less than 1% of patients. Conditional scurvy has also been reported.

Conditional scurvy is reported to occur following excessive doses of ascorbic acid over a prolonged period of time. The mechanism of action for this condition is thought to be that large doses of ascorbic acid condition the patient over time for rapid clearance of ascorbic acid resulting in scurvy. The plasma levels of ascorbic acid appear to remain within normal limits. The actual existence of conditional scurvy remains controversial.

Gastrointestinal

Nausea, diarrhea, and abdominal cramps appears to be associated with doses exceeding 2 g per day, although there have been some reports with as little as 1 g per day.

Esophagitis appears to be associated with prolonged or increased contact of ascorbic acid tablets with the esophageal mucosa.

Gastrointestinal side effects have included nausea, diarrhea, abdominal cramps, and esophagitis.

Hematologic

Hematologic side effects have included hemolysis.

The majority of hemolysis reports have been associated with patients who have concurrent glucose-6-phosphate dehydrogenase deficiency.

Local

Local side effects have included transient mild soreness at the site of injection.

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