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Asclera Side Effects

Generic Name: polidocanol

Note: This page contains information about the side effects of polidocanol. Some of the dosage forms included on this document may not apply to the brand name Asclera.

Not all side effects for Asclera may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to polidocanol: intravenous foam, intravenous solution

In addition to its needed effects, some unwanted effects may be caused by polidocanol (the active ingredient contained in Asclera). In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking polidocanol, check with your doctor or nurse immediately:

More common
  • Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • collection of blood under the skin of the injection site
  • deep, dark purple bruise at the injection site
Incidence not known
  • Anxiety
  • blue-green to black skin discoloration
  • blurred vision
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • chest pain
  • cough
  • darkening of the skin
  • difficult or labored breathing
  • difficulty with swallowing
  • dizziness or lightheadedness
  • fainting
  • fast, irregular, pounding, or racing heartbeat or pulse
  • fever
  • inability to speak
  • increased hair growth in the treatment area
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • loss of consciousness
  • nerve injury
  • no blood pressure or pulse
  • noisy breathing
  • pain, redness, or sloughing of the skin at the injection site
  • pain, redness, or swelling in the arm or leg
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • seizures
  • severe or sudden headache
  • shortness of breath
  • skin rash
  • slurred speech
  • sores, welting, or blisters
  • stopping of the heart
  • sudden shortness of breath or troubled breathing
  • temporary blindness
  • tightness in the chest
  • unconsciousness
  • unusual tiredness or weakness
  • weakness in the arm or leg on one side of the body, sudden and severe
  • wheezing

Some of the side effects that can occur with polidocanol may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Incidence not known
  • Confusion
  • feeling of warmth
  • redness of the face, neck, arms, and occasionally, upper chest
  • sudden sweating

For Healthcare Professionals

Applies to polidocanol: injectable solution

Local

Local side effects have included injection site hematoma, irritation, discoloration, pain, pruritus, warmth, thrombosis, necrosis and neovascularization.

Hypersensitivity

Hypersensitivity side effects have included anaphylactic shock and angioedema.

Respiratory

Respiratory side effects have included dyspnea and asthma.

Cardiovascular

Cardiovascular side effects have included cardiac arrest, deep vein thrombosis, pulmonary embolism, vasovagal syncope, circulatory collapse, vasculitis and palpitations.

Nervous system

Nervous system side effects have included cerebrovascular accident, migraine, paresthesia (local), loss of consciousness, confusional state, nerve injury, and dizziness.

Dermatologic

Dermatologic side effects have included generalized urticaria, skin hyperpigmentation, dermatitis allergic, and hypertrichosis (in the area of sclerotherapy).

General

General side effects have included pyrexia and hot flush.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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