Articadent Side Effects

Generic name: articaine / epinephrine

Note: This document contains side effect information about articaine / epinephrine. Some of the dosage forms listed on this page may not apply to the brand name Articadent.

Some side effects of Articadent may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to articaine / epinephrine: injectable solution

Get emergency medical help if you have any of these signs of an allergic reaction while taking articaine / epinephrine: hives; difficulty breathing; swelling or puffiness of your face, lips, tongue, or throat.

Tell your caregivers at once if you have a serious side effect such as:

  • weak or shallow breathing;

  • slow heart rate, weak pulse;

  • feeling like you might pass out;

  • swelling in your face;

  • swollen or bleeding gums;

  • anxiety, confusion, restless feeling, tremors or shaking;

  • blurred vision, ringing in your ears; or

  • seizure (convulsions).

Less serious side effects of articaine / epinephrine may include:

  • tongue pain or swelling, mouth sores;

  • nausea, vomiting, constipation, diarrhea, upset stomach;

  • increased thirst, drooling;

  • nervousness, dizziness, drowsiness;

  • ear pain, neck pain, joint or muscle pain;

  • unusual or unpleasant taste in your mouth;

  • numbness or tingly feeling;

  • mild skin rash or itching; or

  • runny nose, sore throat.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

For Healthcare Professionals

Applies to articaine / epinephrine: injectable solution

Other

Other side effects including pain (up to 13%), headache (up to 5%), positive blood aspiration into syringe (3.2%), swelling (2.7%), face edema (1%), infection (1%), neck pain, abdominal pain, ear pain, taste perversion, and accidental injury have been reported.

Gastrointestinal

Gastrointestinal side effects including nausea and emesis (1.6%), gingivitis (1%), constipation, diarrhea, dyspepsia, glossitis, gum hemorrhage, mouth ulceration, nausea, stomatitis, tongue edema, tooth disorder, and vomiting have been reported.

Musculoskeletal

Musculoskeletal side effects including trismus (1.6%), arthralgia, myalgia, back pain, and osteomyelitis have been reported.

General

General side effects including sleepiness (1.1%), malaise, and asthenia have been reported.

Nervous system

Nervous system side effects including paresthesia (1%), numbness and tingling (1%), dizziness, dry mouth, facial paralysis, hyperesthesia, increased salivation, nervousness, neuropathy, paresthesia, somnolence, and exacerbation of Kearns-Sayre syndrome have been reported.

Persistent paresthesias of the lips, tongue, and oral tissues have been reported with use of articaine, with slow, incomplete, or no recovery. These events have been reported chiefly following nerve blocks in the mandible and have involved the trigeminal nerve and its branches.

Cardiovascular

Cardiovascular side effects including palpitation (1.0%), hemorrhage, migraine, syncope, tachycardia, and elevated blood pressure have been reported.

Respiratory

Respiratory side effects including pharyngitis, rhinitis, sinus pain, and sinus congestion have been reported.

Hematologic

Hematologic side effects including ecchymosis and lymphadenopathy have been reported.

Metabolic

Metabolic side effects including edema and thirst have been reported.

Local

Local side effects including injection site pain and a burning
sensation above the injection site have been reported.

Dermatologic

Dermatologic side effects including pruritus and skin disorder have been reported.

Genitourinary

Genitourinary side effects including dysmenorrhea have been reported.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.

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