Aristocort Side Effects

Generic Name: triamcinolone

Note: This page contains information about the side effects of triamcinolone. Some of the dosage forms included on this document may not apply to the brand name Aristocort.

Not all side effects for Aristocort may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to triamcinolone: injection suspension

In addition to its needed effects, some unwanted effects may be caused by triamcinolone (the active ingredient contained in Aristocort). In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking triamcinolone, check with your doctor or nurse immediately:

More common
  • Aggression
  • agitation
  • anxiety
  • blurred vision
  • decrease in the amount of urine
  • dizziness
  • fast, slow, pounding, or irregular heartbeat or pulse
  • headache
  • irritability
  • mental depression
  • mood changes
  • nervousness
  • noisy, rattling breathing
  • numbness or tingling in the arms or legs
  • pounding in the ears
  • shortness of breath
  • swelling of the fingers, hands, feet, or lower legs
  • trouble thinking, speaking, or walking
  • troubled breathing at rest
  • weight gain
Incidence not known
  • Abdominal cramping and/or burning (severe)
  • abdominal pain
  • backache
  • bloody, black, or tarry stools
  • cough or hoarseness
  • darkening of skin
  • decreased vision
  • diarrhea
  • dry mouth
  • eye pain
  • eye tearing
  • facial hair growth in females
  • fainting
  • fatigue
  • fever or chills
  • flushed, dry skin
  • fractures
  • fruit-like breath odor
  • full or round face, neck, or trunk
  • heartburn and/or indigestion (severe and continuous)
  • increased hunger
  • increased thirst
  • increased urination
  • loss of appetite
  • loss of sexual desire or ability
  • lower back or side pain
  • menstrual irregularities
  • muscle pain or tenderness
  • muscle wasting or weakness
  • nausea
  • pain in back, ribs, arms, or legs
  • painful or difficult urination
  • skin rash
  • sleeplessness
  • sweating
  • trouble healing
  • trouble sleeping
  • unexplained weight loss
  • unusual tiredness or weakness
  • vision changes
  • vomiting
  • vomiting of material that looks like coffee grounds

Some of the side effects that can occur with triamcinolone may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Incidence not known
  • Blemishes on the skin
  • bruising
  • dry, scaly skin
  • feeling of constant movement of self or surroundings
  • full or bloated feeling
  • increased appetite
  • increased hair growth on the face, forehead, back, arms, and legs
  • large, flat, blue, or purplish patches in the skin
  • pimples
  • pitting or depression of the skin at the injection site
  • reddish purple lines on the arms, face, legs, trunk, or groin
  • redness of the skin
  • redness, swelling, tenderness, or pain at the injection site
  • sensation of spinning
  • small, red, or purple spots on the skin
  • thin, fragile, or shiny skin
  • thinning of the scalp hair

For Healthcare Professionals

Applies to triamcinolone: compounding powder, inhalation aerosol, inhalation aerosol with adapter, injectable suspension, oral tablet

Cardiovascular

Cardiovascular side effects have included fluid retention, sodium retention, congestive heart failure, potassium loss, hypokalemic alkalosis, and hypertension.[Ref]

Musculoskeletal

Musculoskeletal side effects have included aseptic necrosis of femoral and humeral heads, calcinosis (following intra-articular or intra-lesional use), Charcot-like arthropathy, loss of muscle mass, muscle weakness, osteoporosis, pathologic fracture of long bones, postinjection flare (following intra-articular use), steroid myopathy, tendon rupture, and vertebral compression fractures. Postmarketing experience has included very rare reports of bone mineral density loss and osteoporosis, especially with prolonged use, which may lead to an increased risk of fractures.[Ref]

Decreases in bone density of the total hip and the trochanter have been reported with the use of inhaled triamcinolone acetonide in a study (n=109) of premenopausal women with asthma. The yearly change in bone density at the total hip and the trochanter showed a greater decline as the number of puffs per day of the inhaled glucocorticoid increased.[Ref]

Gastrointestinal

Gastrointestinal side effects have included peptic ulcer with potential perforation and hemorrhage, perforation of small and large bowel, pancreatitis, abdominal distention, and ulcerative esophagitis.[Ref]

Dermatologic

Dermatologic side effects have included impaired wound healing, thin, fragile skin, petechiae and ecchymoses, facial erythema, increased sweating, and suppressed reactions to skin tests.[Ref]

Nervous system

Nervous system side effects have included convulsions, increased intracranial pressure with papilledema, vertigo, and headache.[Ref]

Endocrine

Endocrine side effects have included development of cushingoid state, menstrual irregularities, suppression of growth in children, manifestations of latent diabetes, increased requirements for insulin or oral hypoglycemic agents in diabetics, decreased carbohydrate tolerance, and secondary adrenocortical and pituitary unresponsiveness.[Ref]

Ocular

Ocular side effects have included posterior subcapsular cataracts, increased intraocular pressure, glaucoma, and exophthalmos. Retinal and choroidal occlusion as a complication after posterior sub-Tenon triamcinolone (the active ingredient contained in Aristocort) injection has been reported.[Ref]

Metabolic

Metabolic side effects have included negative nitrogen balance due to protein catabolism.[Ref]

Hypersensitivity

Hypersensitivity side effects have included anaphylactoid reactions, anaphylaxis, and angioedema.

Other

Other side effects have included abnormal fat deposits, decreased resistance to infection, hiccups, increased or decreased motility and number of spermatozoa, moon face, malaise, and weight gain.

Local

Local side effects have included injection site infections following non-sterile administration.

References

1. "Product Information. Aristospan (triamcinolone)" Fujisawa, Deerfield, IL.

2. Burge S "Should inhaled corticosteroids be used in the long term treatment of chronic obstructive pulmonary disease?" Drugs 61 (2001): 1535-44

3. Israel E, Banerjee TR, Fitzmaurice GM, Kotlov TV, LaHive K, LeBoff MS "Effects of inhaled glucocorticoids on bone density in premenopausal women." N Engl J Med 345 (2001): 941-7

4. Moshfeghi DM, Lowder CY, Roth DB, Kaiser PK "Retinal and choroidal vascular occlusion after posterior sub-tenon triamcinolone injection." Am J Ophthalmol 134 (2002): 132-4

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