Alka-Seltzer Original Side Effects

Generic Name: aspirin / citric acid / sodium bicarbonate

Note: This page contains information about the side effects of aspirin / citric acid / sodium bicarbonate. Some of the dosage forms included on this document may not apply to the brand name Alka-Seltzer Original.

Not all side effects for Alka-Seltzer Original may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Applies to aspirin / citric acid / sodium bicarbonate: oral tablet, oral tablet effervescent

Along with its needed effects, aspirin / citric acid / sodium bicarbonate may cause some unwanted effects. Although the following side effects occur very rarely when 1 or 2 doses of this combination medicine is taken occasionally, they may be more likely to occur if: too much medicine is taken, the medicine is taken several times a day, or the medicine is taken for more than a few days in a row.

You should check with your doctor immediately if any of these side effects occur when taking aspirin / citric acid / sodium bicarbonate:

Signs of overdose in children
  • Changes in behavior
  • drowsiness or tiredness (severe)
  • fast or deep breathing
  • Any loss of hearing
  • bloody urine
  • confusion
  • convulsions (seizures)
  • diarrhea (severe or continuing)
  • difficulty in swallowing
  • dizziness, lightheadedness, or feeling faint (severe)
  • drowsiness (severe)
  • excitement or nervousness (severe)
  • fast or deep breathing
  • flushing, redness, or other change in skin color
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • nausea or vomiting (severe or continuing)
  • shortness of breath, troubled breathing, tightness in chest, or wheezing
  • stomach pain (severe or continuing)
  • swelling of eyelids, face, or lips
  • unexplained fever
  • uncontrollable flapping movements of the hands (especially in elderly patients)
  • vision problems

If any of the following side effects occur while taking aspirin / citric acid / sodium bicarbonate, check with your doctor or nurse as soon as possible:

Less common or rare
  • Bloody or black, tarry stools
  • frequent urge to urinate
  • headache (severe or continuing)
  • increased blood pressure
  • loss of appetite (continuing)
  • mood or mental changes
  • muscle pain or twitching
  • ringing or buzzing in ears (continuing)
  • skin rash, hives, or itching
  • slow breathing
  • swelling of face, fingers, ankles, feet, or lower legs
  • unpleasant taste
  • unusual tiredness or weakness
  • vomiting of blood or material that looks like coffee grounds
  • weight gain (unusual)

Some of the side effects that can occur with aspirin / citric acid / sodium bicarbonate may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

  • Heartburn or indigestion
  • increased thirst
  • nausea or vomiting
  • stomach pain (mild)

More about Alka-Seltzer Original (aspirin / citric acid / sodium bicarbonate)

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Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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