AK-Tob Side Effects

Generic name: tobramycin ophthalmic

Medically reviewed by Drugs.com. Last updated on May 23, 2023.

Note: This document contains side effect information about tobramycin ophthalmic. Some dosage forms listed on this page may not apply to the brand name AK-Tob.

Applies to tobramycin ophthalmic: ophthalmic ointment, ophthalmic solution.

Serious side effects of AK-Tob

Along with its needed effects, tobramycin ophthalmic (the active ingredient contained in AK-Tob) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking tobramycin ophthalmic:

Less common

Itching, redness, swelling, or other sign of eye or eyelid irritation not present before use of this medicine

Symptoms of overdose

Increased watering of the eyes
itching, redness, or swelling of the eyes or eyelids
painful irritation of the clear front part of the eye

Other side effects of AK-Tob

Some side effects of tobramycin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Burning or stinging of the eyes

Eye ointments usually cause your vision to blur for a few minutes after application.

For Healthcare Professionals

Applies to tobramycin ophthalmic: ophthalmic ointment, ophthalmic solution.

General

The most frequently reported side effects included localized ocular toxicity and hypersensitivity reactions.^[Ref]

Ocular

Common (1% to 10%): Conjunctival erythema, eye itching, lacrimation, lid itching, lid swelling, ocular discomfort, ocular hyperemia, punctate keratitis

Uncommon (0.1% to 1%): Blurred vision, conjunctival disorder, dry eye, eye discharge, eye pain, eye pruritus, eyelid disorder, eyelid edema, eyelid erythema, keratitis, lacrimation increased, visual impairment

Frequency not reported: Burning of the eyes, eye allergy, eye irritation, eyelid pruritus, stinging of the eyes^[Ref]

Hypersensitivity

Common (1% to 10%): Hypersensitivity reactions

Frequency not reported: Anaphylactic reaction^[Ref]

Dermatologic

Uncommon (0.1% to 1%): Dermatitis, dry skin, leukoderma, madarosis, pruritus, urticaria

Frequency not reported: Erythema multiforme, rash, Stevens-Johnson syndrome^[Ref]

Other

Frequency not reported: Increased systemic toxicity^[Ref]

The risk of systemic toxicity is higher in patients receiving systemic aminoglycosides concurrently; total serum concentration monitoring should be considered in this population.^[Ref]

Local

Localized ocular toxicity included conjunctival erythema, eye itching, lacrimation, lid itching, lid swelling, ocular hyperemia, and punctate keratitis.^[Ref]

Common (1% to 10%): Localized ocular toxicity

Uncommon (0.1% to 1%): Corneal abrasion, foreign body sensation in eyes^[Ref]