Afrinol Side Effects

Generic Name: pseudoephedrine

Please note - some side effects for Afrinol may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects by Body System

Cardiovascular

Pseudoephedrine causes vasoconstriction which generally does not produce hypertension, but may be problematic for patients with preexisting hypertension. Arrhythmias may be produced in predisposed patients. Rarely, pseudoephedrine has been reported to cause coronary artery spasm and chest pain.

One report evaluated the effect with 60 mg of pseudoephedrine on individuals in a hyperbaric chamber at 1 atmosphere (simulated scuba dive to 66 feet of sea water). Pseudoephedrine and depth (simulated) were found to have significant but opposite effects on heart rate, although these effects were unlikely to be clinically significant during diving.

Cardiovascular side effects have included tachycardia. Some patients have developed hypertension and/or arrhythmias.

Nervous system

Nervous system side effects have included insomnia in up to 30% of patients. Tremor, anxiety, nervousness, and headache have also been reported.

Gastrointestinal

Gastrointestinal side effects have included anorexia and gastric irritation in approximately 5% of patients. Dry mouth, nose, or throat have occurred in up to 15% of patients.

Hypersensitivity

Hypersensitivity side effects have included fixed drug eruptions.

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