Advate Side Effects
Generic Name: antihemophilic factor
Note: This page contains information about the side effects of antihemophilic factor. Some of the dosage forms included on this document may not apply to the brand name Advate.
Not all side effects for Advate may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to antihemophilic factor: intravenous powder for solution
In addition to its needed effects, some unwanted effects may be caused by antihemophilic factor (the active ingredient contained in Advate). In the event that any of these side effects do occur, they may require medical attention.
You should check with your doctor immediately if any of these side effects occur when taking antihemophilic factor:More common
- Changes in facial skin color
- fast or irregular breathing
- puffiness or swelling of the eyelids or around the eyes
- sensation of burning, warmth, heat, numbness, tightness, or tingling
- skin rash, hives, or itching
- tightness in the chest
- troubled breathing
- unusual tiredness or weakness
- Bluish color of the fingernails, lips, skin, palms, or nail beds
- blurred vision
- chest pain or discomfort
- deep or fast breathing with dizziness
- difficult or labored breathing
- difficulty with swallowing
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- fast, pounding, or irregular heartbeat or pulse
- noisy breathing
- numbness of the feet, hands, and around the mouth
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- slow or irregular heartbeat
- swelling of the face, throat, or tongue
- unusual tiredness or weakness
Some of the side effects that can occur with antihemophilic factor may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common
- Burning, stinging, or swelling at the place of injection
- dizziness or lightheadedness
- dry mouth or bad taste in the mouth
- lack or loss of strength
- redness of the face
- Change in taste
- loss of taste
- Abdominal or stomach pain
- feeling of warmth
- increased sweating
- muscle or bone pain
- redness of the eye
- redness of the face, neck, arms, and occasionally, upper chest
- redness of the skin
- trouble seeing
For Healthcare Professionals
Applies to antihemophilic factor: intravenous kit, intravenous powder for injection
Nervous system side effects have included headache, dizziness, somnolence, and asthenia.[Ref]
Respiratory side effects have included dyspnea and rhinitis.[Ref]
Musculoskeletal side effects have included arthralgia.[Ref]
Local side effects have included injection site pain.[Ref]
General side effects have included pyrexia and chills.[Ref]
Gastrointestinal side effects have included nausea, diarrhea, and vomiting.[Ref]
Dermatologic side effects have include pruritus, rash, and urticaria.[Ref]
Cardiovascular side effects have included hemorrhage, hypotension, and vasodilatation.[Ref]
1. "Product Information. Koate-HP (antihemophilic factor)." Bayer, West Haven, CT.
2. "Product Information. Helixate FS (antihemophilic factor)." CSL Behring, King of Prussia, PA.
3. "Product Information. Humate-P (antihemophilic factor-von Willebrand factor)." CSL Behring, King of Prussia, PA.
4. "Product Information. Xyntha (antihemophilic factor)." Wyeth Laboratories, Philadelphia, PA.
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