Priority approval for Alimta -- first drug for treatment of malignant pleural mesothelioma
Priority approval for Alimta -- first drug for treatment of malignant pleural mesothelioma ROCKVILLE, MD., February 5, 2004 -- The FDA today approved Alimta (pemetrexed disodium) for use in combination with cisplatin for the treatment...

Chemo for Mesothelioma Offers Limited Survival Benefits
THURSDAY, May 15 -- Adding chemotherapy to other treatments being giving to patients with mesothelioma, a lung cancer usually linked to asbestos exposure, does not appear to improve either survival or quality of life. Malignant pleural mesothelioma...

Lung Cancer Trial Targets Asbestos-Related Disease
MONDAY, July 21 -- Patients are being recruited for a clinical trial of a new targeted radiation and chemotherapy protocol for pleural mesothelioma, a cancer of the lung's lining that's almost always caused by exposure to asbestos. Currently, the standard treatment is to remove the affected...

Immune Cells Shrink Tumors in Mice
...human cancers. The lab-altered T-cells zeroed in on mesothelin, a still mysterious protein produced in abundance by all pancreatic cancers and mesotheliomas, as well as many ovarian and non-small-cell lung cancers. The protein is believed to play a role in the spread and growth of cancer cells,...

Alimta (pemetrexed for injection) First Agent Approved in Europe as Maintenance Therapy for Advanced, Nonsquamous Non-Small Cell Lung Cancer
' October 15, 2007, American Cancer Society, http://www.cancer.org/docroot/CRI/content/CRI_2_4_1x_What_Is_Non-- Small_Cell_Lu- ng_Cancer.asp?rnav=cri,...

FDA Grants Lilly's Alimta (Pemetrexed for Injection) Third U.S. Approval
' October 15, 2007, American Cancer Society, http://www.cancer.org/docroot/CRI/content/CRI_2_4_1x_What_Is_Non- Small_Cell_Lung_Cancer.asp?rnav=cri, (February...

CytRx Corporation Signs Definitive Agreement to Acquire Innovive Pharmaceuticals, Inc.
...trial for the treatment of subjects with AML and myelodysplastic syndrome (MDS) as well as subjects with non-small cell lung cancer (NSCLC) and mesothelioma. INNO-305 was designed to have a unique ability among WT1 peptide cancer immunotherapeutics to stimulate both CD8 and CD4 T-cells which may...

Clinical Trials Update: Dec. 4, 2008
...----- Pleural Diseases If you are 18 or older with a confirmed diagnosis of malignant pleural mesothelioma, and have failed prior chemotherapy that included pemetrexed with either cisplatin or carboplatin, you may qualify for this study. The research...

Cytrx Corporation Signs Definitive Agreement to Acquire Innovive Pharmaceuticals, Inc.
...trial for the treatment of subjects with AML and myelodysplastic syndrome (MDS) as well as subjects with non-small cell lung cancer (NSCLC) and mesothelioma. INNO-305 was designed to have a unique ability among WT1 peptide cancer immunotherapeutics to stimulate both CD8 and CD4 T-cells which may...

Alimta Approved as Maintenance Therapy for Advanced Lung Cancer
...whose tumor has shrunk or whose cancer has stabilized after chemotherapy. Alimta was first approved in 2004 to treat the asbestos-linked cancer mesothelioma and, later, as an initial therapy for advanced non-small cell lung cancer, the FDA said in a news release. Possible side effects may include...

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