Prometheus to Acquire Lotronex From GlaxoSmithKline
...-- Prometheus Laboratories Inc., a specialty pharmaceutical company has signed an agreement with GlaxoSmithKline to acquire exclusive rights to Lotronex(R) (alosetron hydrochloride) Tablets in the United States. Lotronex is the only prescription drug approved by the FDA for use in female patients...

FDA approves restricted re-marketing of Lotronex
FDA approves restricted re-marketing of Lotronex... ROCKVILLE, MD. -- The Food and Drug Administration (FDA) has announced the approval of a supplemental New Drug Application (sNDA) that permits...

but Public Citizen calls Lotronex decision dangerous, risk program weak
...but Public Citizen calls Lotronex decision dangerous, risk program weak WASHINGTON, D.C. -- Reintroducing Lotronex onto the market as announced by the U.S. Food and Drug Administration...

New Guidelines Issued for Management of IBS
...chloride channel activators, notably lubiprostone (Amitiza), are effective for 'constipation-predominant IBS.' 5HT 3 antagonists such as alosetron (Lotronex) relieve symptoms of diarrhea but can cause constipation and colon ischemia, a restriction of blood flow. 5HT 4 agonists, though effective against...

See also: Diarrhea, Irritable Bowel Syndrome

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