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Lotronex
Lotronex (alosetron) blocks the action of a chemical called serotonin in the intestines. This slows the movement of stools (bowel movements) through the intestines. Lotronex is used to treat severe, chronic irritable bowel syndrome (IBS) in women who have had diarrhea as the main symptom for at...
Lotronex
Lotronex is used for: Treating women with severe irritable bowel syndrome (IBS) accompanied by severe diarrhea (usually lasting for 6 months or more). It is only prescribed to women who do not respond to other medicines and is not to be used by women whose main IBS problem is constipation. Certain...
Lotronex
The active ingredient in LOTRONEX Tablets is alosetron hydrochloride (HCl), a potent and selective antagonist of the serotonin 5-HT3 receptor type. Chemically, alosetron is designated as 2,3,4,5-tetrahydro-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]- -1H-pyrido[4,3-b]indol-1-one,-...
Alosetron Hydrochloride
Alosetron Hydrochloride Pronunciation: (a-LOE-se-tron HYE-droe-KLOR-ide) Class: 5î¸HT 3 receptor antagonist Trade Names: Lotronex - Tablets 0.5 mg - Tablets 1 mg Pharmacology Potent and selective serotonin (5î¸HT 3 ) antagonist that inhibits serotonin receptors in the GI...
Prometheus to Acquire Lotronex From GlaxoSmithKline
...-- Prometheus Laboratories Inc., a specialty pharmaceutical company has signed an agreement with GlaxoSmithKline to acquire exclusive rights to Lotronex(R) (alosetron hydrochloride) Tablets in the United States. Lotronex is the only prescription drug approved by the FDA for use in female patients...
Tioga Pharmaceuticals Asimadoline Demonstrates Positive Results in a Phase 2b Clinical Trial for the Treatment of Irritable Bowel Syndrome
...each subtype. For reasons that remain unknown, IBS is a female-predominant disorder, with two-thirds to three-quarters of the subjects being female. Lotronex (alosetron), a selective 5-HT3 receptor antagonist, is the only drug currently approved by the FDA for the treatment of D-IBS; however, due to...
Lotronex
...If constipation resolves, resume alosetron hydrochloride only on the advice of treating physician . Commonly used brand name(s): In the U.S. Lotronex Available Dosage Forms: Tablet Therapeutic Class: Antidiarrheal Pharmacologic Class: Serotonin Receptor Antagonist, 5-HT3 Uses For Lotronex Alosetron...
FDA approves restricted re-marketing of Lotronex
FDA approves restricted re-marketing of Lotronex... ROCKVILLE, MD. -- The Food and Drug Administration (FDA) has announced the approval of a supplemental New Drug Application (sNDA) that permits...
but Public Citizen calls Lotronex decision dangerous, risk program weak
...but Public Citizen calls Lotronex decision dangerous, risk program weak WASHINGTON, D.C. -- Reintroducing Lotronex onto the market as announced by the U.S. Food and Drug Administration...
See also: Diarrhea, Irritable Bowel Syndrome
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