Teniposide Pregnancy and Breastfeeding Warnings
Teniposide is also known as: Vumon
Teniposide Pregnancy Warnings
Teniposide has been assigned to pregnancy category D by the FDA. Animal studies have revealed evidence of embryotoxicity, teratogenicity reduced sperm count and genetic damage to sperm.. There are no controlled data in human pregnancy. Teniposide should only be given during pregnancy when there are no alternatives and benefit outweighs risk. Women of childbearing potential should be advised to avoid becoming pregnant during therapy with teniposide. Young men of reproductive age should be advised of the possibility of compromised ability to father a child and a possibility for birth defects if they do. They should also be advised of the option to store sperm for future artificial insemination.
Teniposide Breastfeeding Warnings
There are no data on the excretion of teniposide into human milk. The manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
References for pregnancy information
- "Product Information. Vumon (teniposide)." Bristol-Myers Squibb, Princeton, NJ.
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