Somatrem Pregnancy and Breastfeeding Warnings
Somatrem is also known as: Protropin
Somatrem Pregnancy Warnings
Somatrem has been assigned to pregnancy category C by FDA. Animal studies have not been reported. There are no controlled data in human pregnancy. Somatrem is only recommended for use during pregnancy when benefit outweighs risk.
One study has suggested that human growth hormone does not cross the placenta in the direction from mother to fetus.
Somatrem Breastfeeding Warnings
Recombinant human growth hormone has been studied as an agent to increase production of milk in mothers of premature infants. No adverse effects were seen in either the mothers or infants and no changes were noted in milk constituents.
There are no data on the excretion of somatrem into human milk. However, it is not expected that somatrem, a large, molecular-weight protein, would be able to pass in any significant amount into breast milk. The manufacturers recommend that caution be used when administering somatrem to nursing women.
References for breastfeeding information
- Milsom SR, Breier BH, Gallaher BW, Cox VA, Gunn AJ, Gluckman PD "Growth hormone stimulates galactopoiesis in healthy lactating women." Acta Endocrinol (Copenh) 127 (1992): 337-43
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