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Salsalate Pregnancy and Breastfeeding Warnings

Salsalate is also known as: Amigesic, Anaflex, Argesic-SA, Disalcid, Marthritic, Mono-Gesic, Salflex, Salsitab

Salsalate Pregnancy Warnings

Salsalate has been assigned to pregnancy category C by the FDA. Animal studies have revealed evidence of teratogenic and embryocidal effects. There are no controlled data in human pregnancy. Salsalate, like other NSAIDs, should be avoided late in pregnancy because it may cause premature closure of the ductus arteriosus. Salsalate is only recommended for use during pregnancy when benefit outweighs risk.

Salsalate Breastfeeding Warnings

There are no data on the excretion of salsalate into human milk. However, salicylic acid, the primary metabolite of salsalate, has been shown to appear in human milk in concentrations approximating the maternal blood level. The manufacturer recommends that caution be used when administering salsalate to nursing women.

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