Rosuvastatin Pregnancy and Breast Feeding Warnings

Rosuvastatin is also known as: Crestor

Overview

Do not use Rosuvastatin if you are pregnant. It may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Rosuvastatin is found in breast milk. Do not breast-feed while taking Rosuvastatin .

Rosuvastatin Pregnancy Warnings

Rosuvastatin has been assigned to pregnancy category X by the FDA. Animal studies have not revealed evidence of teratogenicity. However, other HMG-CoA reductase inhibitors have been associated with teratogenic effects. There are no controlled data in human pregnancy. Rosuvastatin use is considered contraindicated in pregnancy.

Rosuvastatin oral gavage doses of 5, 15, 50 mg/kg/day given to female rats before mating and continuing through day 7 postcoitus result in decreased fetal body weight (female pups) and delayed ossification at the high dose (systemic exposures 10 times human exposure at 40 mg/day based on AUC comparisons).

Rosuvastatin Lactation Warnings

There are no data on the excretion of rosuvastatin into human milk. The manufacturer considers rosuvastatin to be contraindicated during lactation.

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