Pemetrexed Pregnancy and Breastfeeding Warnings

Pemetrexed is also known as: Alimta

Pemetrexed Pregnancy Warnings

Pemetrexed has been assigned to pregnancy category D by the FDA. Animal studies have revealed evidence of fetotoxicity, teratogenicity, and embryotoxicity, as well as reduced male fertility, hypospermia, and testicular atrophy. There are no controlled data in human pregnancy. Pemetrexed should only be given during pregnancy when there are no alternatives and benefit outweighs risk.

Pemetrexed Breastfeeding Warnings

There are no data on the excretion of pemetrexed into human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions due to pemetrexed in nursing infants, it is recommended that nursing be discontinued if the mother is treated with pemetrexed.

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